Results 81 to 90 of about 3,690,639 (348)

Whole genome sequencing identifies candidate genes for familial essential tremor and reveals biological pathways implicated in essential tremor aetiology

EBioMedicine, 2022
Summary: Background: Essential tremor (ET), one of the most common neurological disorders, has a phenotypically heterogeneous presentation characterized by bilateral kinetic tremor of the arms and, in some patients, tremor involving other body regions ...
Lorraine N. Clark, Yizhe Gao, Gao T. Wang, Nora Hernandez, Allison Ashley-Koch, Joseph Jankovic, Ruth Ottman, Suzanne M. Leal, Sandra M. Barral Rodriguez, Elan D. Louis   +9 more
doaj   +1 more source

Why emerging leaders should focus on being good postdoctoral supervisors

FEBS Letters, EarlyView.
Swamped with work and suddenly a new student is waiting at your doorstep for supervision? Great—this is your chance! In this article, we share tips on how postdocs can strengthen their leadership skills while supervising students. This image has been created using DALL·E. Many postdocs work as leaders later in their career.
Hannah Rostalski, Clara Oudenaarden, Miao Tian, Diyavarshini Gopaul, Anita Kurilla, Pelin Gülizar Ersan   +5 more
wiley   +1 more source

Population Data Centre Profile - The Western Australian Data Linkage Branch

International Journal of Population Data Science, 2020
Established in 1995, the Western Australian Data Linkage Branch (DLB) is Australia’s longest running data linkage agency. The Western Australian Data Linkage System (WADLS) employs an enduring linkage model spanning over 60 data collections supported by ...
Steve Hodges, Tom Eitelhuber, Alexandra Merchant, Janine Alan   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members. [PDF]

, 2014
Emerging pathogens undermine initiatives to control the global health impact of infectious diseases. Zoonotic malaria is no exception. Plasmodium knowlesi, a malaria parasite of Southeast Asian macaques, has entered the human population. P.
A Berry, AA Semenya, AK Bei, Angela Siner, Atique M. Ahmed, B Singh, B Singh, Balbir Singh, BE Barber, BE Barber, C Aurrecoechea, C Daneshvar, Chan Woon Lu, CV Jennings, EV Meyer, G Butcher, G Snounou, H Ozwara, Ing Tien Wong, J Cox-Singh, J Cox-Singh, J Cox-Singh, J Cox-Singh, J Langhorne, J Li, J Rayner, Janet Cox-Singh, JC Barrett, JC Rayner, JC Rayner, JP Cramer, JW Barnwell, K Gunalan, K Hayton, Kenji Hirayama, KS Lee, L Excoffier, LH Bannister, LH Miller, LH Miller, M Willmann, MAM Sallum, Matthias Willmann, Miguel M. Pinheiro, MR Galinski, MR Galinski, N Gomez-Escobar, P Librado, Paul C. Divis, Ramlah Zainudin, RW Moon, S Kumar, S Lopaticki, S Nakazawa, Sanjeev Krishna, Sarina K. Singh-Khaira, Scott B. Millar, Sean Lynch, SL Takala, T William, TM DeSimone, WH Tham   +61 more
core   +10 more sources

Towards business integration as a service 2.0 (BIaaS 2.0) [PDF]

, 2011
Cloud Computing Business Framework (CCBF) is a framework for designing and implementation of Could Computing solutions. This proposal focuses on how CCBF can help to address linkage in Cloud Computing implementations.
Chang, V, Walters, RJ, Wills, G
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

FEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang, Naoki Sunagawa, Toma Kashima, Kiyohiko Igarashi, Akimasa Miyanaga, Shinya Fushinobu   +5 more
wiley   +1 more source

Integrated analysis of genetic data with R

Human Genomics, 2006
Genetic data are now widely available. There is, however, an apparent lack of concerted effort to produce software systems for statistical analysis of genetic data compared with other fields of statistics.
Zhao Jing, Tan Qihua
doaj   +1 more source

Genetic analysis of a large Han Chinese family line with schizoaffective psychosis

Heliyon, 2023
To locate the specific susceptibility genes of a high incidence of schizoaffective disease (SAD) with autonomic dominant inheritance, we recruited a family group from Henan Province with a high incidence of SAD, including 19 individuals sampled from five
Liping Zeng, Ziyun He, Di Liu, Kai Li, Kesheng Gu, Qi Sun, Guisen Mei, Yingxue Zhang, Shengkai Yan, Feng Zhang   +9 more
doaj   +1 more source

A comparison of methods for haplotype inference [PDF]

, 2013
This study presents some of the available methods for haplotype reconstruction and evaluates the accuracy and efficiency of three different software programs that utilize these methods. The analysis is performed on the QTLMAS XII common dataset, which is
Hyvönen, Elvira
core