Results 171 to 180 of about 6,712,199 (326)

Assessing characteristics of populations seen at Commission on Cancer facilities using Pennsylvania linked data. [PDF]

open access: yesJNCI Cancer Spectr, 2023
Reed KG   +8 more
europepmc   +1 more source

Introduction to Linked Data

open access: yes, 2019
The learning objective of this presentation is to understand the aims and principles of Linked Data. Concepts covered include Linked Data and the Semantic Web, how ontologies and their structures are expressed, creating RDF triples, and SPARQL. Practical sections of this material include exercises to examine the Wikidata knowledge graph, compare a ...
openaire   +3 more sources

Clinical significance of stratifying prostate cancer patients through specific circulating genes

open access: yesMolecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian   +12 more
wiley   +1 more source

Predicting Mammogram Screening Follow Through with Electronic Health Record and Geographically Linked Data. [PDF]

open access: yesCancer Res Commun, 2023
Davis M   +4 more
europepmc   +1 more source

Observing observatories: web observatories should use linked data

open access: yes, 2013
Web Observatories are a major international scientific collaboration concerned with data sources of a heterogeneous nature, and often quite large. Of course, they are not the first such collaboration; the Web itself was born as a response to a similar ...
Glaser, Hugh
core  

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

open access: yesMolecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita   +1 more
wiley   +1 more source

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