Results 281 to 290 of about 6,712,199 (326)

Developing a research ready population-scale linked data ethnicity-spine in Wales

, 2022
Akbari A, Torabi F, Bedston S, Lowthian E, Abbasizanjani H, Fry R, Lyons J, Owen RK, Khunti K, Lyons RA.   +9 more
europepmc   +1 more source

Libraries and linked data #1: What are linked data?

, 2013
openaire   +1 more source

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Analysis of the impact of COVID-19 on Scotland's care-homes from March 2020 to October 2021: national linked data cohort analysis. [PDF]

Age Ageing
Burton JK, McMinn M, Vaughan JE, Nightingale G, Fleuriot J, Guthrie B.   +5 more
europepmc   +1 more source

Hydrogen sulfide repairs testicular damage induced by heat stress in rats

FEBS Open Bio, EarlyView.
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo, Yupeng Yin, Susu Guo, Xiaoyan Chen, Suyan Xie, Shiqin Chen, Yan Huang   +6 more
wiley   +1 more source

Cohort profile: Understanding the influence of early life environments and health and social service system contacts over time and across generations through the Western Australian Aboriginal Child Health Survey (WAACHS) Linked Data Study. [PDF]

BMJ Open
Mitrou F, Milroy H, Coffin J, Hamilton SL, Brennan-Jones CG, Schurer S, Davis EA, Richmond P, Passmore HM, Pearson G, Brown A, O'Donnell M, Bowen AC, Azzopardi P, Conigrave KM, Downs J, Cooper MM, Ramsey KA, Ferrante A, Johnson SE, Cave L, Vlaskovsky P, Hopkins KD, D'Antoine HA, Wilkes T, Zubrick SR.   +25 more
europepmc   +1 more source

Positive feedback loop between MAPK and aquaporin 7 regulates autophagy and apoptosis induced by palmitate in RIN‐m5f cells

FEBS Open Bio, EarlyView.
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang, Jiang Tan, Xueting He, Yuqin Chen, Guoping Qiu, Mei Yang   +5 more
wiley   +1 more source

Dysfunctional tetraspanin 7 (TSP‐7) in Caenorhabditis elegans promotes; increases in average life‐ & health‐span, stress‐induced survival and motility

FEBS Open Bio, EarlyView.
The C. elegans tetraspanin‐7 (tsp‐7) is a homologue of human CD63, which is a negative regulator of autophagy. The C. elegans strain, tm5761, has a dysfunctional (knockout) tsp‐7 gene. When compared to the wild‐type strain, the tm5761 strain shows increased: life‐ and health‐span; thermotolerance, and stress‐induced locomotion.
Brogan Jones, Laurence Seabra, Francesco Michelangeli   +2 more
wiley   +1 more source