Results 271 to 280 of about 3,440,234 (310)

Comprehensive analysis of SARS-CoV-2 Spike evolution: epitope classification and immune escape prediction. [PDF]

Virus Evol
Teruel NFB, Crown M, Rajsbaum R, Bashton M, Najmanovich R.   +4 more
europepmc   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Household determinants of delayed MMR vaccination: longitudinal analysis using electronic health records in North East London, UK. [PDF]

BMJ Open
Marszalek M, Firman N, Wilk M, Gutierrez A, Smith K, Dezateux C.   +5 more
europepmc   +1 more source

Identifying prognostic targets in metastatic prostate cancer beyond AR

FEBS Open Bio, EarlyView.
Genome‐wide functional screens combined with a large gene expression database and clinical outcomes can identify new therapeutic vulnerabilities in prostate cancer. Eight potentially druggable targets demonstrated strong dependency in cell lines, were associated with worse prognosis clinically, and showed evidence of protein expression in prostate ...
Emily Feng, Eric Feng, Tracy Berg, Isabella S. Nguyen, Lilac G. Nguyen, William Chen, Meng Zhang, David Quigley, Marina Sharifi, Haolong Li, Ilsa Coleman, Peter S. Nelson, Martin Sjöström, Shuang G. Zhao   +13 more
wiley   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Correction: Pooling of primary care electronic health record (EHR) data on Huntington's disease (HD) and cancer: establishing comparability of two large UK databases. [PDF]

BMJ Open
europepmc   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Social norms as influencers of type 2 diabetes risk-taking behaviours: a qualitative deep-dive diagnosis in two high-burden districts in Uganda. [PDF]

BMJ Open
Kiguli J, Matovu JKB, Kasujja FX, Nabaliisa J, Kirunda R, Naggayi G, Wejuli JM, Okade T, Lesley Rose N, Halage A, Mayega RW.   +10 more
europepmc   +1 more source

Analysis of the information retrieval process in databases published as linked open data using the RDB2LOD approach

, 2018
Clayton Martins Pereira, Edberto Ferneda, José Eduardo Santarem Segundo   +2 more
openalex   +1 more source

Linked Open Data by europeana

, 2012
openaire   +2 more sources