Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Antibody-drug conjugates in cancer therapy: current advances and prospects for breakthroughs
Frontiers in Cell and Developmental BiologyAntibody-drug conjugates (ADCs), often referred to as “intelligent biological missiles,” have garnered significant attention in the rapidly evolving landscape of cancer therapy. ADCs represent a sophisticated approach by integrating monoclonal antibodies
Dan Wu +9 more
doaj +1 more source
Phase Transition of DNA-Linked Gold Nanoparticle
, 2002 Melting and hybridization of DNA-capped gold nanoparticle networks are investigated with optical absorption spectroscopy. Single-stranded, 12-base DNA-capped gold nanoparticles are linked with complementary, single-stranded, 24-base linker DNA to form ...
Ching-Hwa Kiang +14 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Antibody–drug conjugate: a newly developed biological missile for tumor treatment
Frontiers in OncologyAntibody–drug conjugates (ADCs) represent one of the most advanced drug configurations under current research, primarily composed of a monoclonal antibody (mAb), a highly potent cytotoxic payload, and a linker that connects the drug to the antibody.
Zhuoran Tang, Yanchun Xie, Yanping Zeng
doaj +1 more source
Elongated and substituted triazine-based tricarboxylic acid linkers for MOFs
Beilstein Journal of Organic Chemistry, 2016 New triazine-based tricarboxylic acid linkers were prepared as elongated relatives of triazinetribenzoic acid (TATB). Additionally, functional groups (NO2, NH2, OMe, OH) were introduced for potential post-synthetic modification (PSM) of MOFs ...
Arne Klinkebiel +3 more
doaj +1 more source
Peer relations linking overweight and obesity, and mediator factors among Turkish adolescents
, 2022 Başak Koca Özer +8 more
openalex +2 more sources
X-Linked Thrombocytopenia with Beta-Thalassemia [PDF]
, 2020 National Cancer Institute
openalex +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Zeolitic Imidazolate Frameworks as H_2 Adsorbents: Ab Initio Based Grand Canonical Monte Carlo Simulation [PDF]
, 2010 We report the H_2 uptake behavior of 10 zeolitic−imidazolate frameworks (ZIFs), based on grand canonical Monte Carlo (GCMC) simulations. The force fields (FFs) describing the interactions between H_2 and ZIF in the GCMC were based on ab initio quantum ...
Choi, Seung-Hoon +2 more
core +1 more source