Results 201 to 210 of about 255,199 (267)
Development of an Optimized CXCR4-Targeting Theranostic Pair. [PDF]
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Software: Practice and Experience, 1982
AbstractLinkers, although a well‐established component of language translation, are typically machine‐dependent, idiosyncratic, and hard for many users to understand. This paper describes a machine‐independent linker and object language. The linker embodies those linking functions that are machine‐independent and centralizes them in a single tool ...
Christopher W. Fraser, David R. Hanson
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AbstractLinkers, although a well‐established component of language translation, are typically machine‐dependent, idiosyncratic, and hard for many users to understand. This paper describes a machine‐independent linker and object language. The linker embodies those linking functions that are machine‐independent and centralizes them in a single tool ...
Christopher W. Fraser, David R. Hanson
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VT-LINKER: Visual-Textual-Knowledge Entity Linker
2020“A picture is worth a thousand words”, the adage reads. However, pictures cannot replace words in terms of their ability to efficiently convey clear (mostly) unambiguous and concise knowledge. Images and text, indeed, reveal different and complementary information that, if combined, result in more information than the sum of that contained in the ...
Dost Shahi +4 more
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New photocleavable linker: α-Thioacetophenone-type linker
Bioorganic & Medicinal Chemistry Letters, 2014Photocleavable linkers are advantageous over the common linkers because they could be cleaved without using reagents. A novel photocleavable linker with an α-thioacetophenone moiety has been developed. This linker, which can be cleaved upon irradiation at 365 nm via the Norrish type II reaction, is applicable to a protein affinity purification system ...
Hirotaka, Yonezawa +6 more
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The Influence of Linkers on Quantum Interference: A Linker Theorem
The Journal of Physical Chemistry C, 2017How heteroatomic substitutions affect electron transport through π-conjugated hydrocarbons has been the subject of some debate. In this paper we investigate the effect of heteroatomic linkers in a molecular junction on the electron-transmission spectrum, focusing on the occurrence of quantum interference (QI) close to the Fermi level, where ...
Yuta Tsuji +3 more
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Molecular Ecology Resources, 2010
AbstractDNA barcoding is based on the use of short DNA sequences to provide taxonomic tags for rapid, efficient identification of biological specimens. Currently, reference databases are being compiled. In the future, it will be important to facilitate access to these databases, especially for nonspecialist users.
Mihai, Albu +3 more
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AbstractDNA barcoding is based on the use of short DNA sequences to provide taxonomic tags for rapid, efficient identification of biological specimens. Currently, reference databases are being compiled. In the future, it will be important to facilitate access to these databases, especially for nonspecialist users.
Mihai, Albu +3 more
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TRAM Linker: A Safety-Catch Linker for the Traceless Release of Acrylamides
Organic Letters, 2004[reaction: see text] A novel safety-catch linker for the solid-phase synthesis of small-molecule libraries containing electrophilic reactive groups has been developed. Upon cleavage from solid support, the linker generates a Michael acceptor (an acrylamide) on each library member.
Christopher J, Ciolli +2 more
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Linker Tailing: Unphosphorylated Linker Oligonucleotides for Joining DNA Termini
DNA, 1984Current procedures for inserting linker oligonucleotides between DNA termini involve terminal addition of linker duplexes followed by restriction enzyme cleavage and religation . Such methods have the disadvantage that target DNA molecules containing internal recognition sites are cut during the linker cleavage step.
R, Lathe +3 more
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Linkers for protein degradation
Nature Chemical Biology, 2018The ability to subvert E3 ubiquitin ligases with small-molecule drugs offers tremendous promise for drug discovery. A new study demonstrates how structural and computational techniques can engineer and exploit unnatural protein–protein interfaces to design selective protein degraders.
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