Results 291 to 300 of about 4,110,454 (393)

Conversion of an agonistic anti-TNFR2 biparatopic antibody into an antagonist by insertion of peptide linkers into the hinge region. [PDF]

J Biol Chem
Otsuki T, Matsumoto S, Fujita J, Miyata T, Namba K, Kanada R, Okuno Y, Kamada H, Ohno H, Akiba H.   +9 more
europepmc   +1 more source

A Particular Case of Sex-linked Inheritance in the Silkworm(Prel.note)

, 1935
Hiroshi Nishikawa
openalex   +2 more sources

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

Molecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause, Rixa‐Mareike Köhn, Christian Ickes, Julia Lenger, Jonas Fischer, Sabrina Cappello, Ivan Bogeski   +6 more
wiley   +1 more source

AI-directed gene fusing prolongs the evolutionary half-life of synthetic gene circuits. [PDF]

Sci Adv
Menuhin-Gruman I, Arbel-Groissman M, Naki D, Bergman S, Tuller T.   +4 more
europepmc   +1 more source

Polyvinyl Alcohol Fiber Cross-linked with Dimethylene Thiourea

, 1950
Ichiro Ikoma, Hiroshi Kato
openalex   +2 more sources

Not just a by‐product: circular DNA molecules derived from V(D)J recombination are linked to worse prognosis in B‐cell leukemia

Molecular Oncology, EarlyView.
Gao et al. report that circular DNA molecules created as by‐products of V(D)J recombination during lymphocyte maturation (ESCs) can replicate and be retained for much longer than previously thought in healthy cells. In BCP‐ALL cells, increased ESC abundance correlates with a greater chance of relapse likely mediated by their ability to induce genome ...
Davide Pradella, Andrea Ventura
wiley   +1 more source

Activation of <i>N</i>-Formyldipeptide-Masked Prodrugs by Human Peptide Deformylase. [PDF]

ACS Chem Biol
Geißen R, Yildirim O, Köhn M, Scheinberg DA, Tan DS.   +4 more
europepmc   +1 more source

Complex Motion Events and Clause Combining in Saamia [PDF]

, 2016
HIEDA, Osamu
core  

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Distance-Dependence of Photo-CIDNP in Biomimetic Tryptophan-Flavin Diads. [PDF]

Angew Chem Int Ed Engl
Theiss T, Musabirova G, Gerhards L, Anisimova IS, Zoller BGE, Nguyen TNH, Denisov D, Schmidt A, Panter S, Weber S, Tegenkamp C, Solov'yov IA, Matysik J, Gulder T.   +13 more
europepmc   +1 more source