Results 81 to 90 of about 3,670 (220)

OUT OF STEP? AGRICULTURAL POLICY AND AFGHAN LIVELIHOODS

Agricultural and Food Policy,
Christoplos, Ian
core  

GS‐9620 alleviates psoriasis‐like inflammation by regulating autophagy in keratinocytes

Animal Models and Experimental Medicine, EarlyView.
Psoriasis is an immune‐mediated inflammatory disease of the skin characterized by excessive proliferation and abnormal differentiation of keratinocytes. GS‐9620 can increase the expression of ATG5, ATG7 and ATG16L1, thereby regulating the autophagy of keratinocytes and inhibiting the secretion of related inflammatory factors.
Yansi Lyu, Wei Zhou, Pei Zhang, Chen Lin, Xin Wen, Zigang Zhao, Guoqiang Zhang, Qian Zhang, Si Chen   +8 more
wiley   +1 more source

Recent advances in the construction of humanized animal models and applications in translational medicine

Animal Models and Experimental Medicine, EarlyView.
Substantial advances have been achieved in the development of humanized mouse models, which have proven highly valuable in evaluating cancer immunotherapies and elucidating the mechanisms of infectious diseases. There is now a growing shift in research toward larger animal models—such as pigs—that offer greater physiological similarity to humans ...
Yanan Lyu, Yong‐Guang Yang, Zheng Hu
wiley   +1 more source

Exploring disaster risk reduction and climate change adaptation from a gender perspective. Insights from Ladakh, India [PDF]

, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Both Disaster Risk Reduction (DRR) and Climate Change Adaptation (CCA) aim at reducing the vulnerabilities and enhancing the capacities of men and women ...
Le Masson, Virginie
core  

Transition or stagnation? : everyday life, food security and recovery in post-conflict northern Uganda

, 2014
This thesis seeks to analyse whether and in what way institutional reconstruction meets the needs, and fits the context, of the population they are meant to serve.
Wairimu, W.W.
core   +1 more source

Nonviral Gold Nanoparticle‐Mediated Delivery of CRISPR‐Cas9 Ribonucleoprotein and Long DNA Transgenes Into Primary Blood Cells

Advanced NanoBiomed Research, EarlyView.
CRISPR/Cas9 has revolutionized the field of gene therapy, but delivery remains an outstanding issue. We propose a nonviral gold‐nanoparticle platform for co‐delivery of CRISPR/Cas9 ribonucleoprotein and long 2.1 kilobase dsDNA transgene constructs. This CRISPR‐AuNP is inexpensive to produce and mediate gene editing and DNA delivery in T cells and CD34+
Rachel A. Cunningham, Karthikeya S. V. Gottimukkala, Daniel D. Lane, Katrina Poljakov, Patricia Lipson, Mark R. Enstrom, Alessandro Rizzi, Aude G. Chapuis, Jennifer E. Adair   +8 more
wiley   +1 more source

Continuities in crisis : everyday practices of disaster response and climate change adaptation in Mozambique

, 2011
Mozambiqueis a poor country located in the South-East coast of Africa. Due to its prevailing poverty and geographical location along the coastline of the Indian Ocean, and downstream of major regional rivers, the country experiences, in average, one ...
Artur, L.
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An Exposition of Intra-bush and Post-bush Experiences of Formerly Abducted Child Mothers in Northern Uganda: Issues in Rehabilitation, Resettlement and Reintegration

This qualitative study explores the intra-bush and post-bush experiences of formerly abducted child mothers (FACM) in Northern Uganda. Critical events in the lives of young women who were abducted as young girls to join rebel soldiers in the recent civil
Ochen, Eric
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Addressing the humanitarian-development divide in Fragile and Conflict-Affected States: What is the United Kingdom’s aid approach towards Yemen’s protracted conflict, and how did it address the humanitarian development divide

, 2017
This study is about addressing the humanitarian-development divide in Fragile and Conflict-Affected States (FCAS). It aims to provide an overall understanding on the topic by studying FCAS, their impact globally, and the approach of the international ...
Al-Mutawakel, Abeer
core  

Advancements in CO2 Capture Technologies: A Review of Amine Absorption and Alternative Methods for Post‐Combustion Integration

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Carbon capture technologies are poised to become one of the primary focuses regarding the achievement of net‐zero emissions by the year 2050. In these technologies, particular attention is given to post‐combustion CO2 capture, which is more easily implemented at existing power stations and other industries.
Satyajit Mukherjee, Ashish Kumar, Mayurkumar P. Patil, Rohit B. Meshram   +3 more
wiley   +1 more source