Results 91 to 100 of about 447,234 (333)

Population pharmacokinetics of TBAJ‐587 and its main metabolites—Evaluation of different loading dose strategies and early dose selection

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Background and Aim The rise of drug‐resistant tuberculosis (TB) poses a need for new drugs and combinations. TBAJ‐587, a new diarylquinoline (DARQ), has shown promising efficacy in preclinical studies. This work aimed to describe the pharmacokinetics (PK) of TBAJ‐587 and its metabolites M2 and M3 after single ascending dosing in healthy volunteers and ...
Albin A. M. Leding   +6 more
wiley   +1 more source

SPA - SIMULAÇÃO DE PROCESSOS EM AQÜÍFEROS PELO MÉTODO DE ELEMENTOS FINITOS EM AMBIENTE LINUX

open access: yesRevista Águas Subterrâneas, 2004
Este trabalho apresenta o desenvolvimento do pacote computacional SPA, destinado à Simulação numérica de Processos em Aqüíferos. O trabalho foi desenvolvido no Laboratório de Hidráulica Computacional (LHC) do Departamento de Hidráulica e Saneamento da ...
Edson Wendland   +3 more
doaj  

Open Invention Network: A Defensive Patent Pool for Open Source Projects and Businesses [PDF]

open access: yesTechnology Innovation Management Review, 2012
This article explores how patents impact innovation within free/libre open source software (F/LOSS) businesses and projects. The number of software patent suits brought each year is increasing and is diverting millions of dollars in funds from developers
Deborah Nicholson
doaj  

Toward Smart Moving Target Defense for Linux Container Resiliency

open access: yes, 2016
This paper presents ESCAPE, an informed moving target defense mechanism for cloud containers. ESCAPE models the interaction between attackers and their target containers as a "predator searching for a prey" search game. Live migration of Linux-containers
Abed, Amr S.   +3 more
core   +1 more source

Population Pharmacokinetics of Clesrovimab in Preterm and Full‐Term Infants

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Clesrovimab is a half‐life extended monoclonal antibody targeting the respiratory syncytial virus fusion protein. Three studies (phase Ib/IIa [MK‐1654‐002], phase IIb/III [CLEVER], and phase III [SMART]) were conducted to evaluate the efficacy, safety, and pharmacokinetics (PK) of clesrovimab in infants.
Ziheng Hu   +8 more
wiley   +1 more source

The outcomes of electronic personal health records in patients with heart failure or coronary artery disease

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1464-1468, April 2025.
Abstract Background There are limited data on the efficacy of smartphone‐based personal health records (PHRs) in patients with cardiovascular disease. This study aimed to examine the processes, outcomes and challenges associated with the implementation of integrated PHRs in patients with heart failure (HF) or coronary artery disease (CAD). Methods This
Kotaro Nochioka   +16 more
wiley   +1 more source

Using fault injection for testing Linux kernel components

open access: yesТруды Института системного программирования РАН, 2018
The paper presents methods aimed to extend coverage of existing tests by systematic and targeted fault injection in Linux kernel. The main goal is to test if kernel components correctly handle abnormal situations. As long as such situations happen seldom
A. . Tsyvarev, A. . Khoroshilov
doaj   +1 more source

Challenges Using Linux as a Real-Time Operating System [PDF]

open access: yes
Human-in-the-loop (HITL) simulation groups at NASA and the Air Force Research Lab have been using Linux as a real-time operating system (RTOS) for over a decade.
Madden, Michael M.
core   +1 more source

Neural Network Models for Solar Irradiance Forecasting in Polluted Areas: A Comparative Study

open access: yesEnergy Science &Engineering, EarlyView.
Pollution‐aware hybrid ensemble model is proposed to forecast solar irradiance across eight diverse cities. The model integrates MLP, RNN, and NARX to handle varying atmospheric pollution levels. The model outperforms state‐of‐the‐art methods with enhanced accuracy and interpretability on standard solar irradiance data set.
Mujtaba Ali   +6 more
wiley   +1 more source

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