Results 61 to 70 of about 447,234 (333)

Targeting WEE1 in ARID1A/TP53 Concurrent Mutant Colorectal Cancer by Exploiting R‐Loop Accumulation and DNA Repair Deficiencies

open access: yesAdvanced Science, EarlyView.
ARID1A, a SWI/SNF complex component, is frequently mutated in colorectal cancer (CRC). CRC with ARID1A/TP53 concurrent mutations shows marked sensitivity to WEE1 inhibition. ARID1A loss induces R‐loop‐mediated replication stress, impairs ATF3 transcription, and amplifies WEE1i‐induced DNA damage, suggesting a promising therapeutic vulnerability ...
Chi Zhang   +17 more
wiley   +1 more source

Linux Driver Verification

open access: yesТруды Института системного программирования РАН, 2018
Linux driver verification is a large application area for software verification methods, in particular, for functional, safety, and security verification. Linux driver software is industrial production code — IT infrastructures rely on its stability, and
D. Beyer, A. K. Petrenko
doaj   +1 more source

Security Implications of Running Windows Software on a Linux System Using Wine [PDF]

open access: yes, 2018
Linux is considered to be less prone to malware compared to other operating systems, and as a result Linux users rarely run anti-malware. However, many popular software applications released on other platforms cannot run natively on Linux.
A Provataki   +11 more
core   +1 more source

Accurate Identification of Protein Binding Sites for All Drug Modalities Using ALLSites

open access: yesAdvanced Science, EarlyView.
ALLSites is a unified sequence‐based framework for identifying proteome‐wide binding sites across all drug modalities. It integrates a gated convolutional network with a transformer architecture to capture residue interactions directly from the sequence.
Minjie Mou   +14 more
wiley   +1 more source

Latency Performance for Real-Time Audio on BeagleBone Black [PDF]

open access: yes, 2014
In this paper we present a set of tests aimed at evaluating the responsiveness of a BeagleBone Black board in real-time interactive audio applications. The default Angstrom Linux distribution was tested without modifying the underlying kernel.
Linux Audio Conference   +3 more
core  

The Real-Time Linux Kernel

open access: yesACM Computing Surveys, 2019
The increasing functional and nonfunctional requirements of real-time applications, the advent of mixed criticality computing, and the necessity of reducing costs are leading to an increase in the interest for employing COTS hardware in real-time domains.
F. Reghenzani, G. Massari, W. Fornaciari
semanticscholar   +1 more source

Machine Learning‐Assisted Infectious Disease Detection in Low‐Income Areas: Toward Rapid Triage of Dengue and Zika Virus Using Open‐Source Hardware

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki   +3 more
wiley   +1 more source

Improved performance of QCD code on ALiCE [PDF]

open access: yes, 2002
We present results for the performance of QCD code on ALiCE, the Alpha-Linux Cluster Engine at Wuppertal. We describe the techniques employed to optimise the code, including the metaprogramming of assembler kernels, the effects of data layout and an ...
Sroczynski, Z.
core   +3 more sources

Autonomous Recognition of Retained Secretions in Central‐Airway Based on Deep Learning for Adult Patients Receiving Invasive Mechanical Ventilation

open access: yesAdvanced Intelligent Systems, EarlyView.
This work presents a deep learning model to autonomously recognize and classify the secretion retention into three levels for patients receiving invasive mechanical ventilation, achieving 89.08% accuracy. This model can be implemented to ventilators by edge computing, whose feasibility is approved.
Shuai Wang   +6 more
wiley   +1 more source

The Art of Bioinformatics Learning in Our Arabic World

open access: yesHighlights in BioScience, 2019
Bioinformatics became a significant field in life sciences that, draws a number of researchers and extends into a wide range of biological disciplines. Rendering bioinformatics analysis techniques are the most desirable skills in a variety of scholarship
Alsamman M. Alsamman
doaj   +1 more source

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