Results 91 to 100 of about 46,026 (251)

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi   +6 more
wiley   +1 more source

Activatable smart contrast agents for photoacoustic imaging

open access: yesSmart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh   +5 more
wiley   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

open access: yesVIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin   +3 more
wiley   +1 more source

Pleomorphic adenoma of the upper lip: Case Report and Insights from Literature

open access: yes
Pleomorphic adenoma (PA) is the most common benign tumor of the salivary glands, accounting for a significant proportion of both major and minor salivary gland neoplasms.
Yugandhara Kale
core  

A review of the relationship between dimensions of alcohol consumption and the burden of disease: 2026 update including Mendelian randomisation studies

open access: yesAddiction, EarlyView.
Abstract Background and aims Evidence on the causal impact and corresponding risk relationships between dimensions of alcohol consumption and health outcomes continues to evolve, with some contradictory findings across study designs. This review aimed to update current knowledge on causality and risk relationships to inform global and national ...
Sinclair Carr   +5 more
wiley   +1 more source

AKR1C3 Binds β‐Trcp to Promote the Degradation of TFRC to Protect Hepatocellular Carcinoma From Ferroptosis

open access: yesCancer Science, EarlyView.
In this study, we show that aldo‐keto reductase family 1 member C3 (AKR1C3), a protein highly expressed in ferroptosis resistant hepatocellular carcinoma cells, acts as an enzyme‐independent scaffold protein by promoting the nuclear export of β‐transducin repeat protein (β‐TrCP) and its binding to transferrin receptor (TFRC) in an enzyme‐independent ...
Lei Qi   +10 more
wiley   +1 more source

Cavernous hemangioma treatment of the lower lip with electrocautery: case report

open access: yes, 2020
Hemangiomas are benign tumors of vascular origin described as an abnormal accumulation of blood vessels in the skin or other organs. They comprise 70% of all benign neoplasias of the oral cavity (often on the lip).
Agra, Débora Maria de Medeiros   +1 more
core  

From Cold to Hot: Nanozyme‐Based Strategies for Reprogramming the Tumour Immunoenvironment

open access: yesCell Proliferation, EarlyView.
Nanozymes, with multi‐enzyme catalytic activities, reprogram the immunosuppressive tumour microenvironment by inducing immunogenic cell death, relieving hypoxia, and depleting antioxidants, effectively converting immunologically “cold” tumours into “hot” ones to boost cancer immunotherapy efficacy.
Yue Wang   +9 more
wiley   +1 more source

Assessing patient perception following outpatient dermatological surgical procedures

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Despite receiving similar information about outpatient dermatologic surgical procedures, some patients still hold misconceptions about the nature of their lesions and the treatment. No studies have been done to understand this difference in the perception of surgery.
Ana Morelló‐Vicente   +6 more
wiley   +1 more source

Microcystic Adnexal Carcinoma of the Lower lip: A Case Report

open access: yes, 2008
PURPOSE: Microcystic adnexal carcinoma is a rare malignant appendage tumor, first described by Goldstein et al in 1982. Here, we present our experience in treatment of a case on the lower lip.
나동균, 탁관철
core  

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