Results 51 to 60 of about 253,405 (300)

Cancer Statistics from the Shaukat Khanum Memorial Trust’s Hospital-based Cancer Registry, Pakistan, 1994–2022: An Observational Study

open access: yesJournal of Cancer and Allied Specialties
Introduction: The Shaukat Khanum Memorial Trust (SKMT) has been operational since February 1990. The first Shaukat Khanum Memorial Cancer Hospital and Research Center (SKMCH&RC) started functioning in Lahore on December 29, 1994.
Farhana Badar, Shahid Mahmood
doaj   +1 more source

Topical 5% Imiquimod Sequential to Surgery for HPV-Related Squamous Cell Carcinoma of the Lip

open access: yesMedicina, 2021
Background: Squamous cell carcinoma (SCC) is one of the most common neoplasms affecting the oral cavity and the face. Its more differentiated forms may be associated with human papilloma virus (HPV) infection.
Giovanni Pentangelo   +4 more
doaj   +1 more source

A case of cystic neoplasm of the small lip

open access: yesJournal of obstetrics and women's diseases, 2020
In the gynecological department of the Imperial Clinical Midwifery Institute, a case of cystic formation was observed this year, which had the right labrum in its place; the description of this case is the subject of my report.
openaire   +2 more sources

Mepce Restrains Ferroptosis in Prostate Cancer Through 7SK–P‐TEFb Pause Control

open access: yesAdvanced Science, EarlyView.
Genome‐wide CRISPR screening identifies MEPCE as a pause‐control regulator that restrains ferroptosis in prostate cancer. MEPCE loss releases P‐TEFb/CDK9 from 7SK snRNP control, enhances RNAPII Ser2 phosphorylation, and accelerates NRF2‐HMOX1‐driven labile iron accumulation and lipid peroxidation, revealing a transcriptional kinetic gate that lowers ...
Tongtong Zhang   +9 more
wiley   +1 more source

Ferroptosis Suppression by the M6A Reader IGF2BP1 Underlies Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
IGF2BP1 promotes gemcitabine resistance in pancreatic cancer by stabilizing m6A‐modified FTH1 transcripts and protecting them in stress granules, thereby suppressing ferroptosis. Pharmacological inhibition of IGF2BP1 disrupts this protective pathway, restores ferroptotic sensitivity, and enhances gemcitabine efficacy in resistant tumors.
Ying‐Qin Zhu   +10 more
wiley   +1 more source

Resources for oral health in Africa

open access: yesFrontiers in Oral Health
Oral health in Africa is often overlooked despite its substantial impact on overall health and well-being. Currently, Africa has a very high prevalence of dental diseases, including untreated dental caries in permanent teeth, severe periodontal disease ...
Moréniké Oluwátóyìn Foláyan   +7 more
doaj   +1 more source

Treatment of oral hemangioma with sclerotherapy: case report

open access: yesJornal Vascular Brasileiro, 2014
Hemangiomas are benign neoplasms that are common in the head and neck, but relatively rare in the oral cavity. They can cause esthetic and functional impairment, depending on location.
Salomão Israel Monteiro Lourenço Queiroz   +4 more
doaj   +1 more source

Oncocytic carcinoma of lip: A rare neoplasm of minor salivary gland

open access: yesJournal of Cytology, 2012
Oncocytic carcinoma is an extremely rare neoplasm of the salivary gland, with only a few cases reported in literature till date. We report the occurrence of this rare lesion in lip in a 43-year-old female presenting with a progressively increasing swelling for which excision was done.
Sonia Chhabra   +3 more
openaire   +3 more sources

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li   +21 more
wiley   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv   +16 more
wiley   +1 more source

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