Results 141 to 150 of about 71,327 (302)

Anti‐Obesity Pharmacotherapy and Emerging Multimodal Interventions for Obstructive Sleep Apnea

Chronic Diseases and Translational Medicine, EarlyView.
Cellular and molecular mechanisms of obesity‐related obstructive sleep apnea (OSA). ADMA: asymmetric dimethyrarginine, NLRP3: nucleotide‐binding domain, leucine‐rich repeat family, Pyrin domain containing 3, TLR: toll‐like receptors, IL‐1β: interleukin‐1β, IL‐6: interleukin‐6; LPS: lipopolysacharide, ROS: reactive oxygen species, TNF‐α.
Anish Preshy, Cornelius J. Fernandez, Mohammad Hamid Nedai, Joseph M. Pappachan   +3 more
wiley   +1 more source

Structural and Functional Properties of Ingredient Composition in Kenkey Preparation: A Review

ChemFoodChem, EarlyView.
This review synthesizes three decades of research on kenkey, a fermented maize staple of West Africa. Examining the structural, functional, and nutritional properties that emerge from traditional fermentation and thermal processing, and identifying priorities for future research toward quality standardization and commercial development. ABSTRACT Kenkey,
Afia Sakyiwaa Amponsah
wiley   +1 more source

Xylose Acetals ‐ a New Class of Sustainable Solvents and Their Application in Enzymatic Polycondensation

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Novel organic solvents with an unmodified carbohydrate core were synthesised both from D‐xylose and directly from biomass and were successfully used as reaction media for lipase biocatalysts to synthesise aliphatic and aromatic polyesters. Abstract The use of organic solvents in academic research and industry applications is facing increasing ...
Anastasia O. Komarova, Cicely M. Warne, Hugo Pétremand, Laura König‐Mattern, Johannes Stöckelmaier, Chris Oostenbrink, Georg M. Guebitz, Jeremy Luterbacher, Alessandro Pellis   +8 more
wiley   +1 more source

Redox Biocatalysis in Lidocaine‐Based Hydrophobic Deep Eutectic Solvents: Non‐Conventional Media Outperform Aqueous Conditions

ChemSusChem, Volume 18, Issue 6, March 15, 2025.
Two hydrophobic DESs, lidocaine/oleic acid and lidocaine/decanoic acid, were utilized as reaction media that were enzyme‐compatible and highly substrate‐solubilizer for carbonyl reduction catalyzed by horse liver alcohol dehydrogenase, focusing on the effect of water contents and on maximizing substrate loadings, which showcases for the first time the ...
Ningning Zhang, Viktoria Lahmann, Jan Philipp Bittner, Pablo Domínguez de María, Sven Jakobtorweihen, Irina Smirnova, Selin Kara   +6 more
wiley   +1 more source

Total Synthesis of Novel Oxylipins: Plasmodiophorols A, C, and Epimers

European Journal of Organic Chemistry, EarlyView.
The first total syntheses of plasmodiophorols A and C, recently identified α‐linolenic acid‐derived oxylipins, were achieved from chiral cyclopentafuranone in 12–13 steps. The routes use enzymatic desymmetrization, epimerization, and diastereoselective Grignard addition, providing stereocontrolled access to the natural products and reliable standards ...
Alexandre Guy, Aurélien Lebrun, Thierry Durand, Camille Oger   +3 more
wiley   +1 more source

Porcine Liver Esterase‐Catalyzed Dynamic Kinetic Resolution of a Lactone‐Bridged Biaryl: Impact of Organic Cosolvents on Enantioselectivity

European Journal of Organic Chemistry, EarlyView.
A stereolabile lactone‐bridged biaryl enables dynamic kinetic resolution to provide a conformationally stable ring‐opened biaryl. A significant positive effect of water‐immiscible organic cosolvents on the enantioselectivity in a reaction catalyzed by porcine liver esterase has been discovered for the first time.
Neha Dhiman, Anke Hummel, Kyohei Kanomata, Yoshinari Sawama, Tohru Taniguchi, Harald Gröger, Shuji Akai   +6 more
wiley   +1 more source

Evaluation of lipases in the desymmetrization of meso-exo-3,5-dihydroxymethylenetricyclo[5.2.1.0 2,6]decane and the synthesis of chiral derivatives

Journal of the Brazilian Chemical Society, 2004
meso-exo-3,5-dihydroxymethylenetricyclo[5.2.1.0(2,6)]decane was efficiently desymmetrized by the lipase from Pseudomonas cepacia (PS-C 'Amano' II) in vinyl acetate in high yields (93%) and with excellent enantiomeric excesses (ee > 99% by chiral GC ...
Costa Valentim E. U, Pohlmann Adriana R, Sordi Marli L. T. de   +2 more
doaj  

Hydrolytic Enzymes' Fingerprints in Surface and Deep‐Sea Prokaryotic Communities in the Ross Sea: A Metagenomic Approach

Environmental DNA
The Ross Sea is characterized by a significant export of particulate organic carbon, with up to 50% of surface primary production being transferred to deep water layers.
Rita Varchetta, Elisa Banchi, Federica Cerino, Vincenzo Manna, Alessandro Vezzi, Fabio De Pascale, Donata Canu, Mauro Celussi   +7 more
doaj   +1 more source

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Recent Progress on Enzyme Immobilization: Materials, Strategies, and Applications

Food Bioengineering, EarlyView.
Enzyme immobilization technology has undergone substantial evolution driven by advances in materials science. This review systematically examines the recent advances in enzyme immobilization since 2024, with a focused analysis of five major categories of enzyme carriers including covalent organic framework, metal‐organic frameworks, polymers, carbon ...
Shuran Wang, Ruoke Li, Yixuan Xie, Hanya Zhang, Xiaoyu Huang, Siwei Chen, Weixin Xu, Yueling Liu   +7 more
wiley   +1 more source