Results 211 to 220 of about 140,194 (304)

Deep Learning Enables Identification of Antimicrobial Peptides Through Mechanochromic Fingerprints

Angewandte Chemie, EarlyView.
We demonstrate a new platform for antimicrobial peptide identification by combining polydiacetylene, hyperspectral imaging, and deep learning. The trained model classifies distinct spectral fingerprints into 14 peptide classes with 96.79% accuracy, revealing previously hidden molecular information beyond conventional colorimetric sensing.
Jiali Chen, Che‐Lun Chin, Qingzhen Zhu, Ling Chao, Kaori Sugihara   +4 more
wiley   +2 more sources

Effect of cucurbit[7]uril on DPPC-containing liposomes: Interactions with the lipid bilayer. [PDF]

Sci Prog
Altaher S, Alshaer W, Al Adaileh F, Nsairat H, Alsotari S, Rababah MH, Al Bawab A, Odeh F.   +7 more
europepmc   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

Advanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia, Akshay Pandey, Raffaele Spanò, Bianca Martins Estevão, Roberto Palomba, Greta Avancini, Tamaghna Gupta, Ana Maria Lopez Estevez, Stuart B. Goodman, Nidhi Bhutani, Paolo Decuzzi   +10 more
wiley   +1 more source

Localized Accumulation of Tri‐n‐Propylamine Prolongs Electrochemiluminescence for Tumor Model Spheroid Analysis

Angewandte Chemie, EarlyView.
Here, we enhance the electrochemiluminescence imaging of cellular spheroids using [Ru(bpy)3]2+/TPrA chemistry. Our strategy, which involves pre‐incubation with TPrA, enables high‐resolution, long‐term visualization of cellular spheroids without phototoxicity.
Vanshika Gupta, Megan L. Hill, Samuel P. Nortz, Yashvi Choudhary, Ashutosh Rana, Jeffrey E. Dick   +5 more
wiley   +2 more sources

Optogenetic actin network assembly on lipid bilayer uncovers the network density-dependent functions of actin-binding proteins. [PDF]

Nat Commun
Yamamoto K, Miyazaki M.
europepmc   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Direct insertion of an ion channel immobilized on a soft agarose gel bead into a lipid bilayer: an optimized method. [PDF]

Anal Sci
Asakura M, Wang S, Hirano M, Ide T.
europepmc   +1 more source

Translocation of penetratin-like peptides involving calcium-dependent interactions between glycosaminoglycans and phosphocholine headgroups of the membrane lipid bilayer. [PDF]

RSC Chem Biol
He B, Khemaissa S, Cardon S, Marquant R, Illien F, Ravault D, Burlina F, Sachon E, Walrant A, Sagan S.   +9 more
europepmc   +1 more source

Chaotropic Agent-Assisted Supported Lipid Bilayer Formation. [PDF]

Langmuir
Cawley JL, Santa DE, Singh AN, Odudimu AT, Berger BA, Wittenberg NJ.   +5 more
europepmc   +1 more source

An all-atom model of the human cardiac sodium channel in a lipid bilayer. [PDF]

Sci Rep
Knotts GM, Lile SK, Campbell EM, Agee TA, Liyanage SD, Gwaltney SR, Johnson CN.   +6 more
europepmc   +1 more source