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Nanoparticle–lipid bilayer interactions studied with lipid bilayer arrays

Nanoscale, 2015
Cationic and anionic polystyrene nanoparticles were screened for lipid bilayer interactions with different solutions, bilayer compositions, and particle charges.
Tyler Smith, Bin Lu, Jacob J. Schmidt
openaire   +3 more sources

Water and Lipid Bilayers

2015
Water is crucial to the structure and function of biological membranes. In fact, the membrane's basic structural unit, i.e. the lipid bilayer, is self-assembled and stabilized by the so-called hydrophobic effect, whereby lipid molecules unable to hydrogen bond with water aggregate in order to prevent their hydrophobic portions from being exposed to ...
Jonathan D. Nickels, John Katsaras
openaire   +3 more sources

Texture of Lipid Bilayer Domains

Journal of the American Chemical Society, 2009
We investigate the texture of gel (g) domains in binary lipid membranes composed of the phospholipids DPPC and DOPC. Lateral organization of lipid bilayer membranes is a topic of fundamental and biological importance. Whereas questions related to size and composition of fluid membrane domain are well studied, the possibility of texture in gel domains ...
Jensen, Uffe Bernchou   +5 more
openaire   +4 more sources

Long-Range Ordering of Blunt-Ended DNA Tiles on Supported Lipid Bilayers.

Journal of the American Chemical Society, 2017
Long-range ordering of DNA crossover tiles with blunt ends on lipid bilayers is investigated using atomic force microscopy. "Blunt-ended" tiles do not have single-stranded complementary ends, and thus instead of assembling via base-pairing, they can ...
N. Avakyan, J. W. Conway, H. Sleiman
semanticscholar   +1 more source

Molecular Simulations of Mixed Lipid Bilayers with Sphingomyelin, Glycerophospholipids, and Cholesterol.

Journal of Physical Chemistry B, 2017
The highly diversified composition of lipid bilayers across living cells is crucial for many biological processes. Lipid bilayers mainly consist of phosphatidylcholines (PC), phosphatidylethanolamines (PE), sphingomyelin (SM), and cholesterol, with ...
Indrani Bera, Jeffery B. Klauda
semanticscholar   +1 more source

Properties of Poloxamer Molecules and Poloxamer Micelles Dissolved in Water and Next to Lipid Bilayers: Results from Computer Simulations.

Journal of Physical Chemistry B, 2016
To study the properties of poloxamer molecules P85 and P188 and micelles containing these poloxamers in bulk water and also next to lipid bilayers, we performed coarse-grained molecular dynamics computer simulations.
U. Adhikari   +3 more
semanticscholar   +1 more source

Paclitaxel Partitioning into Lipid Bilayers

Journal of Pharmaceutical Sciences, 1996
Paclitaxel (taxol) is diterpenoid anticancer drug with a new mechanism of cytostatic action. It is under investigation in clinical trials for treatment of various types of human cancer. A major difficulty in developing paclitaxel as a chemotherapeutic agent in its poor water solubility.
Wenk, M. R.   +3 more
openaire   +3 more sources

Functional dynamics of deuterated β2 -adrenergic receptor in lipid bilayers revealed by NMR spectroscopy.

Angewandte Chemie, 2014
G-protein-coupled receptors (GPCRs) exist in conformational equilibrium between active and inactive states, and the former population determines the efficacy of signaling.
Yutaka Kofuku   +7 more
semanticscholar   +1 more source

Lipid bilayer on a droplet: Formation of lipid bilayers on a droplet array

2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS), 2012
This paper describes a method for the formation of a lipid bilayer on a droplet-based chamber array. This method enables us to form small chambers sealed with lipid bilayers easily. The lipid membranes are stable and remain for at least 1 day. We successfully observed a transmembrane phenomenon via the lipid membrane on a droplet by fluorescent ...
Taishi Tonooka, Shoji Takeuchi
openaire   +2 more sources

Effect of methyl-branched fatty acids on the structure of lipid bilayers.

Journal of Physical Chemistry B, 2014
Methyl-branched fatty acids are widespread in prokaryotic membranes. Although anteiso and iso branching (that is on the antepenultimate and penultimate carbons) and the presence of multiple methyl branches in the phytanoyl chain are known to modify the ...
David Poger, Bertrand Caron, A. Mark
semanticscholar   +1 more source

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