Results 251 to 260 of about 1,222,168 (350)

Roles of lactylation in lipid metabolism and related diseases. [PDF]

Cell Death Discov
Zhao B, Lan Z, Li C, Wang H.
europepmc   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Novel Strategies against Hepatocellular Carcinoma through Lipid Metabolism. [PDF]

Oncol Res
Yang Y, Zhao P, Chen H, Tu Y, Zhou Y, Liu X, Sreang L, Zhou Z, Tu J.   +8 more
europepmc   +1 more source

Exposure to leachates of plastic food containers disturbs glucose and lipid metabolism: Insights from models mimicking real-exposure scenarios

Hu Liu, Peiqi Li, Zhoujin Tan, Ziqi Yu, Weigao Zhang, Yunfeng Zhu, Jiayi Xu, Xiaoxiao Wu, Jing Li, Chi Zhang, Lei Chen, Dan Weng   +11 more
openalex   +1 more source

Multiphysics‐Driven Assembly of Biomimetic Vesicles

Advanced Materials, EarlyView.
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko, Ian Gimino, Aastha Chandiwala, Bayan Alkotoub, Ali Bashiri Dezfouli, Heiko Reith, Asjad Bakhtiar, Rojda Hicsanmaz, Johann Brenner, Christoph J. O. Kaiser, Elena Belli, Shilpi Pandey, Samuel D. Rabkin, Kornelius Nielsch, Gabriele Multhoff, Oliver Hayden, Morteza Hasanzadeh Kafshgari   +16 more
wiley   +1 more source

Fueling the fire-a pan-cancer analysis of MYC-regulated lipid metabolism. [PDF]

Front Cell Dev Biol
Chatterjee T, Beffert E, Liefwalker D.
europepmc   +1 more source

Treatment Resistant Persister Cells Exploit Macrophage Lipid Metabolism to Sustain Glioblastoma Growth

Avirup Chakraborty, Yang Changlin, Aryeh Silver, Diana Feier, Guimei Tian, Avinash Pittu, Christina A. Von Roemeling, Nagheme Thomas, Michael Andrews, Cole Conforti, Olusegun O. Sobanjo, Nyla Searl, Miruna Anica, Raquel G. McTiernan, Maryam Rahman, Jianping Huang, Jeffrey K. Harrison, Duane A. Mitchell, Matthew R. Sarkisian, Loic P. Deleyrolle   +19 more
openalex   +1 more source

The Vegan Villain Sets Out to The End of Summer: Functionalized Coatings as Biohybrid UV‐Sensors

Advanced Materials Interfaces, EarlyView.
This study introduces biohybrid coatings incorporating E. coli biomass expressing photoconvertible fluorescent proteins as UV‐A responsive elements. Upon irradiation at 400 nm, the coatings exhibit an irreversible fluorescence shift from green to red within 15 min. Notably, the photoconversion capability is retained after >1 year of storage.
Amelie Skopp, Matea Marosevic, Broder Rühmann, Volker Sieber   +3 more
wiley   +1 more source

Advances in understanding the role of gut microbiota in fat deposition and lipid metabolism. [PDF]

J Anim Sci Biotechnol
Zhong Y, Lei Y, Jiang S, Chen D, Wang X, Wang K, Liao T, Liao R, Gan M, Niu L, Zhao Y, Chen L, Zhou X, Wang Y, Zhu L, Shen L.   +15 more
europepmc   +1 more source

Membrane Semi‐Permeability and Ion Selectivity in Chemiosmosis: Open Systems Volume Dependence of Electrolyte Chemistry

Advanced Materials Interfaces, EarlyView.
Very small cellular compartments can break electroneutrality and harness proton gradients without active transport structures, whereas larger volumes cannot, underscoring why life's critical energy processes are confined in microscopic spaces. ABSTRACT The effect of pH changes in external ionic solutions on liposomes entrapping non‐permeable weak acid ...
Josep M. Ribó, Isabel Herreros, David Hochberg, Federico Morán, Michael Stich   +4 more
wiley   +1 more source