Results 281 to 290 of about 1,222,168 (350)

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

open access: yesAdvanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu   +15 more
wiley   +1 more source

Association between Disorders of Lipid Metabolism and Oculopathy: An Overview. [PDF]

open access: yesInt J Med Sci
Yang Y   +8 more
europepmc   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang   +7 more
wiley   +1 more source

ECM-mimicking hydrogel models of human adipose tissue identify deregulated lipid metabolism in the prostate cancer-adipocyte crosstalk under antiandrogen therapy

open access: gold
Agathe Bessot   +9 more
openalex   +1 more source

Aberrant lipid metabolism reshapes the immune landscape in bone metastasis of nasopharyngeal carcinoma. [PDF]

open access: yesJ Immunother Cancer
Feng Y   +9 more
europepmc   +1 more source

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