Results 111 to 120 of about 7,835,349 (342)

Generation of dynamic structures in nonequilibrium reactive bilayers

open access: yes, 2005
We present a nonequlibrium approach for the study of a flexible bilayer whose two components induce distinct curvatures. In turn, the two components are interconverted by an externally promoted reaction. Phase separation of the two species in the surface
Buceta, Javier   +2 more
core   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Lipid Patterns and Atherogenesis in Cholesterol-Fed Chickens

open access: yesExperimental Biology and Medicine, 1957
Summary1) The degree of atheromatosis in the thoracic aortas and brachiocephalic arteries has been compared with plasma lipid pattern in 255 cholesterol-fed cockerels. Correlation was good with all determined variables except α-lipoprotein cholesterol concentration.
D M, TENNENT   +4 more
openaire   +2 more sources

Studies of cationic amphiphilic drug catalysed membrane degradation [PDF]

open access: yes, 2007
Imperial Users ...
Sebai, Sarra C., Sebai, Sarra C.
core  

Free Energy Calculations of Membrane Permeation: Challenges due to Strong Headgroup-Solute Interactions

open access: yes, 2017
Understanding how different classes of molecules move across biological membranes is a prerequisite to predicting a solute's permeation rate, which is a critical factor in the fields of drug design and pharmacology.
Maibaum, Lutz, Pokhrel, Nihit
core   +2 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Tear film parameters in females with thyroid eye disease and diabetes: an observational study

open access: yesJournal of the Pakistan Medical Association
Objective: To assess different tear film parameters in female patients with thyroid eye disease and diabetes using a single portable device. Method: The observational study was conducted at the College of Applied Medical Sciences, King Saud University,
Mana Alafri Alanazi   +6 more
doaj   +1 more source

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