An NIR‐responsive transdermal hydrogel integrating apple EV nanocargo, berberine, piperine, HOFs, and graphene oxide enables localized osteoarthritis modulation. The platform supports enhanced transdermal delivery together with mild hyperthermia‐associated and redox‐related responses, leading to reduced inflammation and oxidative stress, improved ...
Yu‐Wen Tseng +9 more
wiley +1 more source
Optimising Chlorella vulgaris bioflocculation by Aspergillus Niger pellets and their application in wastewater treatment and lipid production. [PDF]
Mohamed A +3 more
europepmc +1 more source
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz +9 more
wiley +1 more source
Sustainable Nutrient Recovery from Wastewater Mixture to Optimize Microalgal Lipid Production: A Vision of Zero Water Footprint. [PDF]
Mamani Condori MA +4 more
europepmc +1 more source
Gellan gum fluid gel (FG) enables controlled ocular delivery of mesenchymal stromal cell (MSC)‐derived extracellular vesicles (EV). Its shear‐thinning, solid‐liquid‐solid rheology ensures prolonged ocular retention. Sustained MSC‐EV release (∼18% in 6 hrs) supports effective EV ocular delivery.
Seyedmohammad Moosavizadeh +7 more
wiley +1 more source
Adaptive laboratory evolution enhances cell yield and lipid production of <i>Chlorella sorokiniana</i> under mildly cold conditions. [PDF]
Lu SY, Zhang SY, Zhang QG.
europepmc +1 more source
Therapeutic Extracellular Vesicles from Synovial Fibroblast‐Primed MSCs for Osteoarthritis Treatment
EVs derived from the microenvironment of SFs transferred MSCs (miSF‐MSC‐EVs) enhanced the expression of miRNAs that regulate cell migration, cell adhesion, and the TGF‐β signaling pathway, demonstrating superior anti‐inflammatory and cartilage regeneration effects compared to conventional MSC‐EVs.
Seo Jeong Kim +5 more
wiley +1 more source
Sustainable Lipid Production with <i>Cutaneotrichosporon oleaginosus</i>: Insights into Metabolism, Feedstock Valorization and Bioprocess Development. [PDF]
Ringel M +6 more
europepmc +1 more source
Nanoemulsion delivery of a TLR7 agonist enhances safety and promotes colocalization with Leishmania‐infected macrophages in skin lesions, enabling a ∼2‐log reduction in parasite burden. However, tissue‐level constraints and TLR‐driven regulatory feedback generate a mixed immune response that limits complete parasite clearance.
Carmen Palomino‐Cano +11 more
wiley +1 more source
Improved neutral lipid production from Tetradesmus obliquus through fed-batch mixotrophic cultivation at high pH using potato peel hydrolysate. [PDF]
Gomaa M +3 more
europepmc +1 more source

