Results 261 to 270 of about 102,476 (312)
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FEEDING FREQUENCY AND LIPOGENESIS IN UNDERNUTRITION
Canadian Journal of Physiology and Pharmacology, 1967Rats were fed either normal or subnormal amounts of a 60% carbohydrate (sucrose) diet for 12–14 days. Food was available to the control animals at all times and was presented to the undernourished rats either all at once, under which conditions it was eaten in 1–2 hours, or hourly in 24 small aliquots.
C, Cohn, D, Joseph
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Regulation of Lipogenesis in Animal Tissues
1974Publisher Summary This chapter discusses the regulation of lipogenesis in animal tissues. Lipid is an essential component of all living cells, and a large group of lipids contain long-chain fatty acids in their molecules. Among fatty acid-containing lipids, glycerolipids are the most abundant; in them, fatty acids are esterified to glycerol.
S, Numa, S, Yamashita
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Inhibition of hepatic lipogenesis by salicylate
Toxicology, 1982Salicylate has been found to be an inhibitor of fatty acid synthesis in isolated rat hepatocytes. Half-maximal inhibition of fatty acid synthesis occurs at approximately 2 mM. The inhibitory effect of salicylate on fatty acid synthesis is not relieve by the addition of acetate, suggesting that salicylate inhibits the conversion of acetate into fatty ...
A C, Beynen +3 more
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Inhibitory mechanisms in the control of lipogenesis
Biochimica et Biophysica Acta (BBA) - Specialized Section on Lipids and Related Subjects, 1963Synthesis of fatty acids by supernatant prepared from livers of fed rats was measured when various cytoplasmic particles of livers from fed or fasted rats were present. Microsomal inhibition of lipogenesis occurs at the acetyl-CoA carboxylase (acetyl-CoA:CO2 ligase (ADP), EC 6.4.1.2) step and involves at least two mechanisms: The action of a microsomal
H M, KORCHAK, E J, MASORO
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Role of glucocorticoids in the regulation of lipogenesis
The FASEB Journal, 1989Traditionally, the glucocorticoids have been viewed as catabolic hormones. However, with the present knowledge about how the glucocorticoid receptor protein functions in the stimulation of mRNA synthesis, a new view must be accepted: These steroids also have an anabolic function. They are anabolic because they stimulate the de novo
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Chemical genetics in tumor lipogenesis
Biotechnology Advances, 2018Since cancer cells depend on de novo lipogenesis for energy supply, highly active membrane biosynthesis and signaling, enhanced fatty acid synthesis is a crucial characteristic of cancer cells. Hence, targeting lipogenic enzymes and signaling cascades is a very promising approach in developing innovative therapeutic agents for the fight against cancer.
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Hormonal Control of Hepatic Lipogenesis
1979Hepatic lipogenesis is subject to both fine (short-term) and coarse (long-term) control mechanisms. Coarse control, i.e., adaptive change in enzyme quantity, is recognized as being important for nutritional and hormonal control of lipogenesis (for reviews see Gibson, Lyons, Scott, and Muto, 1972; Goodridge, 1975; Lakshmanan, Nepokroeff, and Porter ...
R A, Harris +4 more
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