Results 201 to 210 of about 166,338 (256)
DAMPs, PAMPs, and Alarmins: From Mechanism to Therapy
This review synthesizes the expanding biology of PAMPs and DAMPs, from their molecular sources and sensing mechanisms to regulatory networks that govern inflammation and homeostasis. Spanning from classical immune activation to trained immunity and interorgan communication, we highlight the interplay between PAMPs and DAMPs and their context‐dependent ...
Xuanxuan Yu +6 more
wiley +1 more source
Applications of Mesenchymal Stromal Cells for Treatment of Diseases
This schematic summarizes the major therapeutic mechanisms of MSCs across different disease systems and highlights factors associated with MSCs dysfunction, together with current strategies to enhance MSCs function and therapeutic efficacy. This summary diagram illustrates that MSCs exert therapeutic effects in various diseases through multiple ...
Dongmei Xue, Yongsheng Li, Lei Wu
wiley +1 more source
Abstract Background Non‐motor symptoms, especially autonomic dysfunction, are major contributors to disability and decreased quality of life in Parkinson's disease (PD). Despite being common and having a wide range of clinical facets, exocrine gland dysfunction is still not well recognized and managed.
Renato P. Munhoz +2 more
wiley +1 more source
We developed a multimodal large language model‐enabled framework for the early detection, self‐screening, and personalized management of major musculoskeletal disorders, including osteoarthritis (OA), rheumatoid arthritis (RA), and osteoporosis (OP).
Pengyuan Xu +32 more
wiley +1 more source
We report a rare case of pulmonary M. fortuitum infection associated with achalasia that improved following treatment of achalasia alone. ABSTRACT Pulmonary infection caused by Mycobacterium fortuitum is uncommon and often occurs in patients with underlying conditions such as achalasia.
Hidetaka Masuda +5 more
wiley +1 more source
Characterisation of Haemolytic Uropathogenic Escherichia coli Isolated From Dogs and Cats
The present study characterises 51 canine and feline haemolytic E. coli isolates from urinary tract infections by a polyphasic approach, including susceptibility testing, CH‐clonotyping, and DNA microarrays. The majority of isolates belonged to phylogenetic group B2 and were classified as extraintestinal pathogenic E.
Sarah Büttner +12 more
wiley +1 more source
ABSTRACT Vegetables anchor healthy‐diet recommendations yet are the principal nonoccupational route by which residues of organophosphate (OP), pyrethroid, neonicotinoid, organochlorine (OC), and glyphosate herbicide enter the diet, with the gut microbiota a plausible mediator linking these residues to functional gastrointestinal (GI) and inflammatory ...
Chengqian Ye +3 more
wiley +1 more source
A lytic phage cocktail targeting CRKP–CRAB mixed biofilms was systematically evaluated through in vitro, device‐associated, and in vivo models. Integrated transcriptomic analysis revealed molecular responses underlying biofilm disruption, providing mechanistic insights and experimental evidence supporting phage cocktails as a promising strategy against
Xuefang Ren +9 more
wiley +1 more source

