Results 301 to 310 of about 864,255 (364)

The association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) and risk of prostate cancer: a retrospective study. [PDF]

PeerJ
Bu K, Wang J, Zheng X, Zhang K, Wang D, An H, Tao N.   +6 more
europepmc   +1 more source

The Association between Lipoprotein(a) and Coronary Artery Calcification in Elderly Patients with Diabetes: A Cross-Sectional Study. [PDF]

Rev Cardiovasc Med
Qiu L, Qiao H.
europepmc   +1 more source

Characterization of lipoprotein composition and function in pediatric psoriasis reveals a more atherogenic profile [PDF]

, 2015
Admani, S, Eichenfield, LF, Mehta, NN, Natarajan, B, Playford, M, Tom, W   +5 more
core  

Inflammatory and lipemic response to red meat intake in women with and without Rheumatoid Arthritis: a single meal study within a randomized controlled trial. [PDF]

BMC Nutr
Sällström T, Bärebring L, Hulander E, Gjertsson I, Winkvist A, Lindqvist HM.   +5 more
europepmc   +1 more source

Case Report: Cerebral venous sinus thrombosis in the setting of iron deficiency anemia and a high level of lipoprotein (a) in a child. [PDF]

Front Pediatr
Bustamante YY, Seebeck U, Bührlen M, Overberg D.   +3 more
europepmc   +1 more source

Association of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio with coronary heart disease: Establishment and validation of a clinical nomogram model. [PDF]

Medicine (Baltimore)
Ding W, Li T, Fang C, Zhang XX, Wang E.
europepmc   +1 more source

Effects of Cholesterol on the Breast Cancer Resistance Protein: Studies through the Synthesis and Biological Evaluation of Chemical Tools

ChemMedChem, EarlyView.
This study explores the role of cholesterol in the regulation of the efflux pump ABCG2. Substrates and inhibitors of ABCG2, cholesterol linked to fluorescents probes were synthesized and tested to investigate the influence of cholesterol on ABCG2 inhibition and to track cholesterol trafficking on cells.
Ingrid Fatima Zattoni, Bruna Estelita Rugisnk, Isadora da Silva Zanzarini, Alan Guilherme Gonçalves, Vivian Rotuno Moure, Glaucio Valdameri, Ahcène Boumendjel   +6 more
wiley   +1 more source

Estimated sdLDL-C as a biomarker of hepatic steatosis severity in MASLD: a retrospective study. [PDF]

BMC Gastroenterol
Jiang S, Zhang F, Yang H, Han X, Mao J, Zheng G, Fan Y.   +6 more
europepmc   +1 more source

Target‐Mediated Modeling of Alirocumab in Adolescents and Children ≥8 to <12 Years of Age Using Phase II and III Data

Clinical Pharmacology in Drug Development, EarlyView.
Abstract A population pharmacokinetic (PK) covariate analysis was conducted utilizing data from adolescents and children ≥8 to <12 years of age with heterozygous familial hypercholesterolemia. One phase II and 1 phase III study were analyzed (121 patients on active treatment).
Pavel Kovalenko, Lutz Harnisch, Jeanne Mendell, Yuhuan Wang, John D. Davis, Albert Thomas DiCioccio   +5 more
wiley   +1 more source

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

Clinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou, Rohit Rao, Monica E. Shapiro, Nessy Tania, Cody Herron, Cynthia J. Musante, Jim H. Hughes   +6 more
wiley   +1 more source