Results 111 to 120 of about 21,997 (216)

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Aspirin use, lipoprotein(a), and calcific aortic valve disease: the Multi-ethnic Study of Atherosclerosis. [PDF]

Eur Heart J
Razavi AC, Bhatia HS, Marrero N, Dzaye O, Post WS, Nasir K, Tsai M, Vaccarino V, Vasan RS, Thanassoulis G, Tsimikas S, Sperling LS, Budoff MJ, Blumenthal RS, Blaha MJ, Whelton SP.   +15 more
europepmc   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

High Lipoprotein(a) and Valvular and Cardiovascular Events in Patients With Aortic Stenosis: A Meta-Analysis. [PDF]

JACC Adv
Girard AS, Craig N, Thomas PE, Fleury MA, Nordestgaard BG, Clavel MA, Pibarot P, Dweck MR, Kamstrup PR, Arsenault BJ.   +9 more
europepmc   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Investigating the associations between prepregnancy lipoprotein(a) and birth outcomes: The Hispanic Community Health Study/Study of Latinos. [PDF]

J Clin Lipidol
Habib A, Ballou AF, April-Sanders A, Van Wickle K, Meyer ML, Sotres-Alvarez D, Vanterpool YE, Vladutiu CJ, Welch BM, Graff M, Rodriguez CJ, Avery CL.   +11 more
europepmc   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Lipoprotein(a) in cardiovascular disease: pathophysiology, residual risk, and emerging therapeutic strategies. [PDF]

Front Med (Lausanne)
Granata LG, Giubilato S, Campanella F, Amico F, Di Fusco SA, Colivicchi F.   +5 more
europepmc   +1 more source

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Lipoprotein(a) and Prostate Cancer: A Systematic Review of Observational, Genetic and Mendelian Randomization Evidence. [PDF]

Int J Mol Sci
Kisiała M, Bajurny W, Karwacki J, Marcinkowska A, Litarski M, Tulski M, Zawadzki D, Patrzałek P, Gurwin A, Nowak Ł, Krajewski W, Szydełko T, Małkiewicz B.   +12 more
europepmc   +1 more source