Results 41 to 50 of about 17,704 (165)

Molecular pathology of phyllodes tumours of the breast—much more than MED12

Histopathology, EarlyView.
Phyllodes tumours can develop from fibroadenomas bearing MED12 variants by the development of pTERT alterations (“MED12 pathway”) or de novo (“MED12 independent pathway”). Grade progression is associated with increasing genetic complexity including cancer driver gene aberrations. Molecular alterations can be useful in assigning grade and distinguishing
Jia‐Min B Pang, Kylie L Gorringe, Puay Hoon Tan, Stephen B Fox   +3 more
wiley   +1 more source

Clinicopathologic Analysis of Sarcomas in the Oral and Maxillofacial Region: A Systematic Review

Oral Diseases, EarlyView.
ABSTRACT Objective This study aimed to systematically review primary sarcomas in the oral and maxillofacial region, focusing on patient demographics and sarcoma‐specific characteristics, including clinical presentation, histopathology, treatment approaches, outcomes, and survival rates.
Iara Vieira Ferreira, Reydson Alcides de Lima‐Souza, Talita de Carvalho Kimura, Alfio José Tincani, Marcelo Elias Schempf Cattan, Arthur Antolini‐Tavares, Albina Altemani, Fernanda Viviane Mariano   +7 more
wiley   +1 more source

Long‐term results of palliative placement of very low‐axial force self‐expandable metallic stents for malignant colorectal obstruction

DEN Open, Volume 6, Issue 1, April 2026.
Abstract Objectives Stent placement is a standard option for palliative decompression in patients with malignant colorectal obstruction. Long‐term stent placement is associated with perforation, migration, and stent occlusion. Perforation is associated with life expectancy.
Rika Kyo, Takashi Sasaki, Shuntaro Yoshida, Hiroyuki Isayama, Tomonori Yamada, Toshiyuki Enomoto, Yorinobu Sumida, Toshio Kuwai, Masafumi Tomita, Takeaki Matsuzawa, Rintaro Moroi, Toshiyasu Shiratori, Yoshihisa Saida   +12 more
wiley   +1 more source

Survival and prognostic factors among different types of liposarcomas based on SEER database

Scientific Reports
The aim of this study is to elucidate the disparities in survival and risk factors among different subtypes of liposarcoma, through analysis of epidemiological and prognostic data.
Jiaqi Zhao, WenLi Du, XiaoLiang Tao, AiAi Li, Yi Li, Shuai Zhang   +5 more
doaj   +1 more source

A Case of Gastric Atypical Lipomatous Tumor/Well‐Differentiated Liposarcoma With Endoscopic Morphological Changes

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Atypical lipomatous tumor/well‐differentiated liposarcoma is a locally aggressive mesenchymal neoplasm composed of adipocytes and stromal cells. Gastric cases are exceedingly rare, and their malignant potential remains unclear. We report a case of a woman in her 60s who was found to have multiple submucosal tumor‐like lesions of the stomach ...
Rika Omote, Shizuma Omote, Hiroshi Sonobe, Ryosuke Hamano, Tatsuya Toyokawa, Shinya Otsuka, Takehiro Tanaka, Hiroyuki Yanai, Masaru Inagaki, Hidetaka Yamamoto   +9 more
wiley   +1 more source

A highly adhesive and melatonin-loaded PEG hydrogel prevents tumor recurrence and promotes wound healing for tumor-resection wound management of liposarcoma

Materials Today Bio
Liposarcoma is the most common soft tissue sarcoma, and the surgical resection is the primary treatment. However, liposarcoma recurrence and delayed wound healing remain critical challenges due to extensive surgical interventions.
Yonghui Liang, Jianyang Shan, Chen Tan, Zhen Pan, Zhaohui Li, Xiang Fei, Gen Wen, Qingcheng Yang, Dongdong Cheng   +8 more
doaj   +1 more source

High dietary fiber is associated with improved outcomes in patients with melanoma and sarcoma treated with immunotherapy regardless of gut microbiome dysbiosis and social vulnerability

Cancer, Volume 132, Issue 6, 15 March 2026.
ABSTRACT Background Social vulnerability, dietary fiber, and the gut microbiome have been individually implicated in clinical outcomes for melanoma and sarcoma patients. This study hypothesized that increasing social vulnerability is associated with insufficient dietary fiber intake and negatively associated with microbiome composition and clinical ...
Brittany C. Fields, Raymond S. Traweek, Kai Jiang, Russell G. Witt, Ashish Damania, Yi‐Ju Chiang, Nadim Ajami, Elise Nassif‐Haddad, Emily Z. Keung, Manoj Chelvanambi, Xiaotao Zhang, Christine B. Peterson, Jennifer A. Wargo, Carrie R. Daniel, Christina L. Roland, Ashley M. Holder   +15 more
wiley   +1 more source

The first case of rectal myxoid liposarcoma identified by FUS-DDIT3 fusion, presenting as a submucosal tumor with erosion

Human Pathology: Case Reports, 2018
We experienced a 58-year-old Japanese female complaining of bleedings at defecation for about one year. Endoscopy revealed an Ip submucosal tumor (SMT) at the rectum.
Hiroshi Kono, Yoshitane Tsukamoto, Shohei Matsuo, Hideki Hashidate, Hiroyuki Shibuya, Takashi Kobayashi, Yasumasa Takii, Seiichi Hirota   +7 more
doaj   +1 more source

Impact of tissue staining and scanner variation on the performance of pathology foundation models: a study of sarcomas and their mimics

The Journal of Pathology: Clinical Research, Volume 12, Issue 2, March 2026.
Abstract Histopathological analysis is considered the gold standard for the diagnosis and prognostication of cancer. Recent advances in AI, driven by large‐scale digitisation and pan‐cancer foundation models, are opening new opportunities for clinical integration.
Binghao Chai, Jianan Chen, Paul Cool, Fatine Oumlil, Anna Tollitt, David F Steiner, Tapabrata Chakraborti, Adrienne M Flanagan, Adrienne M Flanagan, Anna Tollit, Fatine Oumlil, Fernanda Amary, Roberto Tirabosco, Nischalan Pillay, Paul Cool, Adam Levine, Sebastian Brandner, Angela Richard‐Londt, Petra Balogh, Phillipe Taniere, Preethi Gopinath, Neil Sebire, Luis Campos, Thomas Jacques, Sarah Coupland, Katalin Boros, Edmund Cheesman, Elizabeth Halloran, Caroline Glennie, Leona Doyle, Adrian Marino‐Enriquez, Jonathan Davey, Hannah Monaghan, Michael Toss, David Hughes, Malee Fernando, David Leff, Patrick Shenjere, Oisin Houghton, Tom McCulloch, Filomena Medeiros, Ann Sandison, Kalnisha Naidoo, Getnet Demissie, Heena Patel, Uchechi Igbokwe, Graham Thwaites, Keeley Thwaites, Ann Fleming, Mercy Berin, Shyamala Fernandez, Rajesh Nalluri, Zahra Atiyyah, Konrad Wolfe, Victoria Hills, Tomos Saunders, Matilda Ralph, Nicholas Southgate, Francesca Maggiani, Zsolt Orosz, Jennifer Brown, Nick Athanasou, Ian Cook, Sarah Oliver, Peter Davis, Shelley Brown, Jasenka Mazibrada, Nathan Asher, Efren Quilala, Dalian Beaver, Izhar Bagwan, Dawn Whyndham, Khin Thway, Michael Hubank, Janet Shipley   +74 more
wiley   +1 more source

Pattern and Clinical Significance of CA19‐9 Expression in Human Cancer: A Tissue Microarray Study on 14,966 Tumors

Cancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Carbohydrate antigen 19–9 (CA19‐9) is a cell surface glycoprotein widely used as a diagnostic and prognostic serum marker for monitoring pancreatic cancer. The aim of this study was to evaluate the prevalence and clinical relevance of CA19‐9 expression in human cancer. Methods To comprehensively determine the prevalence and clinical
Nina Schraps, Anne Menz, Florian Viehweger, Seyma Büyücek, David Dum, Ria Schlichter, Andrea Hinsch, Christoph Fraune, Christian Bernreuther, Martina Kluth, Claudia Hube‐Magg, Katharina Möller, Viktor Reiswich, Andreas M. Luebke, Patrick Lebok, Sören Weidemann, Guido Sauter, Maximilian Lennartz, Frank Jacobsen, Till S. Clauditz, Andreas H. Marx, Ronald Simon, Stefan Steurer, Baris Mercanoglu, Nathaniel Melling, Thilo Hackert, Eike Burandt, Natalia Gorbokon, Sarah Minner, Till Krech, Florian Lutz, Morton Freytag   +31 more
wiley   +1 more source