Results 41 to 50 of about 24,166 (225)

Intraoperative Evaluation of Sarcoma Surgical Margins With Indocyanine Green Fluorescence Imaging: Results From an Observational Study

Journal of Surgical Oncology, EarlyView.
ABSTRACT Introduction Sarcomas are rare malignancies that affect both adults and children. Surgical removal with negative histopathological margins is the foundation of sarcoma treatment. Failure to achieve negative margins puts patients at risk of local recurrence (LR). LR rates range between 10% and 30%.
Sumail Bhogal, Matthew Gong, William Li, Brenda Diergaarde, Alma Heyl, Clark Roth, Lawrence Garvin II, Alexander Hoffman, Amanda Locker, Ines Lohse, Maria Silvaggio, Stella Lee, Richard McGough, Kurt Weiss   +13 more
wiley   +1 more source

Comprehensive genomic profiling of a unique liposarcoma arising in a patient with Li–Fraumeni syndrome and the novel detection of c-myc amplification: a case report

Diagnostic Pathology, 2022
Background Germline TP53 mutations have been frequently reported in patients with Li–Fraumeni syndrome (LFS), resulting in a predisposition to various malignancies.
Hirofumi Watanabe, Fumiyoshi Fujishima, Toru Motoi, Yayoi Aoyama, Tetsuya Niihori, Masanobu Takahashi, Sho Umegaki, Hisashi Oishi, Hiroshi Tada, Ryo Ichinohasama, Hironobu Sasano   +10 more
doaj   +1 more source

Dedifferentiation in endometrial cancer is associated with HLA‐I silencing that may be restored by IFN‐γ

The Journal of Pathology, EarlyView.
Abstract Dedifferentiated endometrial carcinoma occurs when a prognostically favorable low‐grade endometrial carcinoma transforms into a highly aggressive undifferentiated carcinoma following genomic inactivation of core SWItch/Sucrose Non‐Fermentable (SWI/SNF) complex protein(s).
Antonio De Leo, Madison Wickenberg, Marco Grillini, Camelia Alexandra Coadǎ, Pooja Praveen Kumar, Annie Tong, James Key, Hannah Kim, Felix Kommoss, Mark Carey, Yangxin Fu, Claudio Ceccarelli, Giovanni Tallini, Paul LaPointe, Martin Köbel, Cheng‐Han Lee   +15 more
wiley   +1 more source

Fat‐Containing Soft Tissue Lesions of the Limbs and Body Wall—A Pictorial Essay

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Lipomatous tumours are frequently encountered on imaging. The spectrum of lipomatous tumours ranges from simple lipomas, which can be monitored clinically, to high‐grade liposarcomas, which require timely, multidisciplinary management. The presence of fat within lesions may also be observed in non‐lipomatous tumours, as well as in a variety of
Kai‐Zheong Lim, Cathryn Hui
wiley   +1 more source

A metabolic crosstalk between liposarcoma and muscle sustains tumor growth

Nature Communications
Dedifferentiated and Well-differentiated liposarcoma are characterized by a systematic amplification of the Murine Double Minute 2 (MDM2) oncogene.
Gabrielle Manteaux, Alix Amsel, Blanche Riquier-Morcant, Jaime Prieto Romero, Laurie Gayte, Benjamin Fourneaux, Marion Larroque, Nadège Gruel, Chloé Quignot, Gaelle Perot, Solenn Jacq, Madi Y. Cisse, Pascal Pomiès, Coralie Sengenes, Frédéric Chibon, Maud Heuillet, Floriant Bellvert, Sarah Watson, Sebastien Carrere, Nelly Firmin, Romain Riscal, Laetitia K. Linares   +21 more
doaj   +1 more source

Dedifferentiated Liposarcoma in the Spermatic Cord Finally Diagnosed at 7th Resection of Recurrence: A Case Report and Bibliographic Consideration

Case Reports in Oncology, 2017
Liposarcoma in the spermatic cord is infrequent, and accurate diagnosis of histopathological subtype is often difficult in spite of the importance of differential diagnosis for adequate treatment.
Kento Morozumi, Yoshihide Kawasaki, Yasuhiro Kaiho, Naoki Kawamorita, Fumiyoshi Fujishima, Mika Watanabe, Yoichi Arai   +6 more
doaj   +1 more source

A case of retroperitoneal liposarcoma extending through the inguinal canal to the thigh and lesser trochanter

IJU Case Reports, 2023
Introduction Liposarcoma is the most common retroperitoneal soft tissue tumor. Liposarcomas are often asymptomatic and are discovered after they become huge.
Takahiro Maekawa, Yoshiyuki Yamamoto, Taigo Kato, Koji Hatano, Atsunari Kawashima, Shinichiro Fukuhara, Ryoichi Imamura, Norio Nonomura   +7 more
doaj   +1 more source

Giant paratesticular liposarcoma with lung metastases: a case report and review of the literature

Journal of Medical Case Reports, 2020
Background Due to its rarity, little is known about the clinical presentations and responses to systemic chemotherapies in advanced and/or metastatic cases of paratesticular liposarcoma.
Takuro Noguchi, Toshirou Fukushima, Hiroaki Hara, Nodoka Sekiguchi, Takashi Kobayashi, Takesumi Ozawa, Daisuke Gomi, Tomonobu Koizumi   +7 more
doaj   +1 more source

Evaluating Fine Needle Aspiration Cytology for Diagnostics of Soft Tissue and Bone Tumours

Cytopathology, EarlyView.
Systematic comparison of needle aspiration cytology and histopathology for 503 tumours in soft tissue and bone showed high concordance (positive predictive value 94%–100%, negative predictive value 83%–89%). In this original study, the authors show that FNAC is a safe and non‐invasive method for diagnosing suspected sarcomas, with the main objective to
Amanda Husu, Sandra Wessman, Karin Wallander, Felix Haglund de Flon   +3 more
wiley   +1 more source

Primary retroperitoneal liposarcoma [PDF]

, 2018
Nicolae Testemitanu State University of Medicine and Pharmacy of the Republic of MoldovaIntroduction. Liposarcoma is a common type of soft tissue sarcoma, which occurs most commonly in the extremities (52%), followed by the retroperitoneum (19 ...
Butnari, Valentin, Schiopu, Victor
core   +1 more source