Mannose-6-Phosphate-Tagged Liposomes Exhibit Increased Transcytosis Across Human Blood-Brain Barrier Model. [PDF]
PharmaceuticsDinamarca MC, Sevarika B, McNeil S.
europepmc +1 more source
Advanced Intelligent Discovery, EarlyView.Predictive models successfully screen nanoparticles for toxicity and cellular uptake. Yet, complex biological dynamics and sparse, nonstandardized data limit their accuracy. The field urgently needs integrated artificial intelligence/machine learning, systems biology, and open‐access data protocols to bridge the gap between materials science and safe ...
Mariya L. Ivanova +4 more
wiley +1 more source
A Lipid‐Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells
Angewandte Chemie, EarlyView.A lipid conjugation strategy anchors a manganese Salen complex within phospholipid membranes, yielding stable, catalytically active liposomes. These lipid–metal assemblies efficiently degrade reactive oxygen species (ROS) and enable intracellular redox control in steatotic HepaRG cells, offering a precise route to biomimetic antioxidant design ...
Olav Vestrheim +7 more
wiley +2 more sources
Advanced liposomal nanoplatforms for flavonoid delivery: a mechanistic and comparative perspective in hepatocellular carcinoma. [PDF]
Discov OncolLal P, Patel J.
europepmc +1 more source
Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis
Advanced NanoBiomed Research, EarlyView.Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia +10 more
wiley +1 more source
Supramolecular Polymer‐Surfactant Co‐Assemblies for Multivalent HSV‐1 Inhibition
Angewandte Chemie, EarlyView.Non‐covalent co‐assembly of BTA with antiviral surfactants produces ratio‐dependent morphologies. Fibrous supramolecular polymers exhibit superior HSV‐1 inhibition, revealing multivalent fiber‐virus interactions and highlighting supramolecular co‐assemblies as a powerful strategy for functional biomedical nanomaterials with demonstrated tunable ...
Christian Zoister +12 more
wiley +2 more sources
Current Status and Emerging Trends in Global Research on Liposome Therapy for Hepatocellular Carcinoma: A Bibliometric Analysis. [PDF]
J Hepatocell CarcinomaHong X, Wu Y, Wu X, Huang C, Li C.
europepmc +1 more source
Advanced NanoBiomed Research, EarlyView.Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi +6 more
wiley +1 more source
Comparative evaluation of donepezil-loaded polymeric and liposomal nanoparticles for Alzheimer's disease: biocompatibility, drug release kinetics, and cellular uptake study. [PDF]
RSC AdvTorossian T +5 more
europepmc +1 more source
Retinol-Loaded Mannosylerythritol Lipid Nanoliposome for Enhanced Human Skin Penetration. [PDF]
Skin Res TechnolPark HW, Yoo DS, Jeong CJ, Park SN.
europepmc +1 more source