Results 161 to 170 of about 165,018 (302)

Fatty Acid Deaggregation and Extraction from Vesicles by Serum Albumin Proceeds Via a Dock-and-Load Mechanism. [PDF]

J Phys Chem Lett
Michler S, Schreiber N, Saluja TK, Chan WS, Knösche MG, Hinderberger D.   +5 more
europepmc   +1 more source

Multifunctional gold nanorods and docetaxel-encapsulated liposomes for combined thermo- and chemotherapy

, 2017
Haiying Hua,1,* Nan Zhang,2,3,* Dan Liu,1 Lili Song,1 Tuanbing Liu,2,3 Shasha Li,2,3 Yongxing Zhao2,3 1Academy of Medical and Pharmaceutical Sciences, 2Department of Pharmaceutics, School of Pharmaceutical Sciences, Zhengzhou University, 3Key Laboratory
Song L, Hua H, Li S, Zhang N, Liu D, Liu T, Zhao Y   +6 more
core  

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

Advanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang, Jinghan Zhu, Qian Xiao, Qichun Wei, Xiujing He, Ping Li, Kai Jiang, Yue Liu, Yeting Hu, Weiwei Yu, Chuansheng Guo, Sheng Chen, Jian Zhao, Siqi Dai, Jingsun Wei, Hang Yang, Tongtong Bu, Kefeng Ding, Haiyan Chen   +18 more
wiley   +1 more source

Liposome drug delivery strategies: state-of-the-art for combating bacterial biofilms. [PDF]

Front Microbiol
Lin T, Liu H, He W, Hu W, Jiang H, Xu Z, Wei J, Yang M, Dai H, Xu J.   +9 more
europepmc   +1 more source

Organic Nanozyme‐Embedded Biotherapeutic Thermosensitive Hydrogel for Extracellular GSH Depletion and Postoperative Tumor Suppression

Advanced Science, EarlyView.
A temperature‐sensitive hydrogel loaded with cyanine nanozymes and Escherichia coli is locally injected into postoperative tumor resection beds. Upon light irradiation, synergistic PTT and PDT work with cascaded reactive oxygen species to deplete extracellular GSH, eliminate residual tumor cells, and induce robust antitumor immune responses for ...
Cong Jiang, Zifan Yang, Rong Guo, Meng Suo, Guowei Wang, Dong Chen, Lilin Su, Fuhuan Wang, Shipeng Ning, Kelong Fan, Xuan Wang   +10 more
wiley   +1 more source

Development and Validation of an HPLC-MS/MS Method for Determining BMS-1166, GB-1107, and Enzalutamide in Rat Plasma and Its Application to Pharmacokinetic Studies. [PDF]

Drug Des Devel Ther
Wang S, Lu S, Li G, Qi Y.
europepmc   +1 more source

CHST1 Drives Immunotherapy Resistance in Triple‐Negative Breast Cancer by Orchestrating an Immunosuppressive Microenvironment via the NKRF–CCL20–Macrophage Axis

Advanced Science, EarlyView.
Proposed model of CHST1‐associated immune remodeling in triple‐negative breast cancer. In CHST1‐low tumors, greater nuclear accumulation of NKRF is associated with repression of an NF‐κB‐related CCL20 transcriptional program and an immune‐inflamed microenvironment.
Shu‐Hao Jiang, Xiao‐Han Ying, Ruo‐Qing Wang, Qun Zhang, Li Chen, Zhi‐Ming Shao, Jun‐Jie Li   +6 more
wiley   +1 more source

Erythrocyte Membrane Incorporation Modulates the Stability and Fusion-Associated Behavior of Biomimetic Liposomes. [PDF]

Langmuir
Sousa LR, Sá LV, Hayasaki TG, Freitas LSO, Riske KA, Mendanha SA, Lima EM.   +6 more
europepmc   +1 more source

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Chitosan-modified liposomes for improved oral delivery of dihydromyricetin: synergistic stabilization, pH-responsive release, and markedly enhanced bioaccessibility. [PDF]

Food Chem X
Teng H, Yan M, Chen C, Ai C, Huo H, Chen L.   +5 more
europepmc   +1 more source