Results 361 to 370 of about 338,765 (389)
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Journal of Drug Targeting, 1996
Doxorubicin is a potent antineoplastic agent with activity against numerous human cancers. Encapsulation of doxorubicin inside a liposome alters bioavailability, biodistribution and thus its biological activity significantly. The physical properties of the liposome (size, lipid components and lipid dose) play a major role in determining drug retention ...
P G, Tardi, N L, Boman, P R, Cullis
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Doxorubicin is a potent antineoplastic agent with activity against numerous human cancers. Encapsulation of doxorubicin inside a liposome alters bioavailability, biodistribution and thus its biological activity significantly. The physical properties of the liposome (size, lipid components and lipid dose) play a major role in determining drug retention ...
P G, Tardi, N L, Boman, P R, Cullis
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1995
Liposomes have been used therapeutically to deliver drugs to certain anatomical sites. The use of liposomes to deliver antigens, although not a new concept, has received less attention. At least two vaccines of nearly identical liposome base composition to our vaccines have been tested in humans.
S, Green +7 more
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Liposomes have been used therapeutically to deliver drugs to certain anatomical sites. The use of liposomes to deliver antigens, although not a new concept, has received less attention. At least two vaccines of nearly identical liposome base composition to our vaccines have been tested in humans.
S, Green +7 more
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How Liposomes Diffuse in Concentrated Liposome Suspensions
The Journal of Physical Chemistry B, 2011Building upon the observation that liposomes of zwitterionic lipids can be stabilized against fusion by the adsorption of cationic nanoparticles (Yu, Y.; Anthony, S.; Zhang, L.; Bae, S. C.; Granick, S. J. Phys. Chem. C2007, 111, 8233), we study, using single-particle fluorescence tracking, mobility in this distinctively deformable colloid system, in ...
Yu, Yan +3 more
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2017
Liposomes have come a long way since their conception in the 1960s, when they were envisioned primarily for drug delivery. Besides serving the important function of the delivery of a variety of drugs, liposomes offer a platform for the co-delivery of a range of therapeutic and diagnostic agents with different physicochemical properties.
Bhawani, Aryasomayajula +2 more
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Liposomes have come a long way since their conception in the 1960s, when they were envisioned primarily for drug delivery. Besides serving the important function of the delivery of a variety of drugs, liposomes offer a platform for the co-delivery of a range of therapeutic and diagnostic agents with different physicochemical properties.
Bhawani, Aryasomayajula +2 more
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WIREs Nanomedicine and Nanobiotechnology, 2008
AbstractMany methods of labeling liposomes with both diagnostic and therapeutic radionuclides have been developed since the initial discovery of liposomes 40 years ago. Diagnostic radiolabels can be used to track nanometer‐sized liposomes in the body in a quantitative fashion.
William Thomas, Phillips +2 more
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AbstractMany methods of labeling liposomes with both diagnostic and therapeutic radionuclides have been developed since the initial discovery of liposomes 40 years ago. Diagnostic radiolabels can be used to track nanometer‐sized liposomes in the body in a quantitative fashion.
William Thomas, Phillips +2 more
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Journal of Colloid and Interface Science, 2005
Giant unilamellar vesicles (GUVs) are deposited on glass microfibers. The vesicles adopt the classical "onduloidal" shape of liquid droplets on fibers. They spread by two simultaneous mechanisms: envelopment and emission of a precursor film. This film spreads faster than on a uniform plane surface and eventually stops, signaling the presence of defects
Borghi, Nicolas +3 more
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Giant unilamellar vesicles (GUVs) are deposited on glass microfibers. The vesicles adopt the classical "onduloidal" shape of liquid droplets on fibers. They spread by two simultaneous mechanisms: envelopment and emission of a precursor film. This film spreads faster than on a uniform plane surface and eventually stops, signaling the presence of defects
Borghi, Nicolas +3 more
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2009
Here, we report methods of preparation of liposome vaccine formulations for the entrapment of antigenic peptides and antigen encoding plasmid DNAs. Two examples of liposomal vaccine formulations producing highly effective immune responses are given. Firstly, a formulation with encapsulated antigenic peptides derived from the hepatitis C virus NS4 and ...
Schwendener, R A +3 more
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Here, we report methods of preparation of liposome vaccine formulations for the entrapment of antigenic peptides and antigen encoding plasmid DNAs. Two examples of liposomal vaccine formulations producing highly effective immune responses are given. Firstly, a formulation with encapsulated antigenic peptides derived from the hepatitis C virus NS4 and ...
Schwendener, R A +3 more
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Stealth Liposomes, Ninja Liposomes, Or Cryptosomes: Are They Really Sterically Stabilized Liposomes?
Journal of Liposome Research, 1992AbstractWhen the idea of putting together a Forum on the subject of polymer and glycan coated liposomes came across my mind, I thought that this would be an unique opportunity for those of us who argue fiercefully in meetings to do the same in writing. The idea was well received when I contacted my colleagues about a year ago.
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Recent advances with liposomes as pharmaceutical carriers
Nature reviews. Drug discovery, 2005V. Torchilin
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