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Comparative Biochemistry of Lipoxygenase Inhibitors

1985
This chapter describes some studies on the mechanism of 5-lipoxygenase regulation and inhibition and then presents an overview of lipoxygenase inhibitors that are active against intact-cell, broken-cell, and purifed enzymes from a variety of sources.
Robert W. Egan, Paul H. Gale
openaire   +1 more source

Effect of a lipoxygenase inhibitor on vasoconstriction in dog lung

American Journal of Physiology-Heart and Circulatory Physiology, 1989
The effects of lipoxygenase inhibition and cyclooxygenase plus lipoxygenase inhibition on the pressor responses to serotonin (5-HT), acetylcholine (ACh), and norepinephrine (NE) were studied in the isolated, blood-perfused dog lung. Bolus doses of 50-250 micrograms 5-HT, 1-5 mumol ACh, and 10-50 micrograms NE were given before and after the ...
H A, el-Kashef   +2 more
openaire   +2 more sources

Endogenous inhibitors of lipoxygenase

European Journal of Pharmacology, 1980
S A, Saeed, M, Drew, H O, Collier
openaire   +2 more sources

[Advances in the research of lipoxygenase inhibitors].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2009
Lipoxygenase is a protein with non-heme iron atom, which has been discovered in many animals and plants. Lipoxygenase which has a close relationship with human tumors, inflammatory diseases, asthma, arteriosclerosis, and toxic action of chemicals could not only di-oxygenate endogenous polyunsaturated fatty acid to yield bioactive factors such as ...
Hong-Xiang, Zhu, Jian-An, Hu
openaire   +1 more source

Cyclooxygenase and lipoxygenase inhibitors in cancer therapy

Prostaglandins, Leukotrienes and Essential Fatty Acids, 1996
G, Ara, B A, Teicher
openaire   +2 more sources

INHIBITORS OF CYCLO-OXYGENASE AND LIPOXYGENASE IN ONIONS

The Lancet, 1988
T, Bayer, H, Wagner, V, Wray, W, Dorsch
openaire   +2 more sources

Tryptamine and homotryptamine-based sulfonamides as potent and selective inhibitors of 15-lipoxygenase

Bioorganic and Medicinal Chemistry Letters, 2005
Zhengxiang Gu   +2 more
exaly  

N-Substituted pyrazole-3-carboxamides as inhibitors of human 15-lipoxygenase

Bioorganic and Medicinal Chemistry Letters, 2015
Mats Larhed, Hans-Erik Claesson
exaly  

Lipoxygenase Inhibitors Prevent Lung Carcinogenesis and Inhibit Non-Small Cell Lung Cancer Growth

Experimental Lung Research, 1998
Terry W Moody   +2 more
exaly  

3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1

Bioorganic and Medicinal Chemistry Letters, 2015
Mats Larhed, Hans-Erik Claesson
exaly  

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