Results 151 to 160 of about 177,363 (264)

Analysis of risk factors for attention deficit hyperactivity disorder among children in Hubei region based on liquid chromatography-tandem mass spectrometry. [PDF]

Front Psychiatry
Hao Y, Ran R, Liu Z, Lu D.
europepmc   +1 more source

Donor‐Cell Senescence Redirects PINK1‐Marked Mitochondrial Cargo From Mitophagy to Microvesicle Transfer Through SUMO3‐Stabilized HSPA9

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicle therapies have been developed for tissue repair, but how donor‐cell senescence reshapes vesicle‐mediated mitochondrial transfer remains unclear. Here, we show that senescent adipose‐derived stem cells (ADSCs) redirect damaged mitochondria into microvesicles (MVs), converting protective vesicles into pro‐degenerative ...
Zixuan Ou, Mingke Zhao, Zhiwei Ling, Lianqi Peng, Bide Tong, Huaizhen Liang, Hongchuan Wang, Di Wu, Yifan Du, Zhi Du, Shihao Zhang, Yuyuan Jia, Yifan Qian, Gan Xu, Liuliang He, Gang Li, Shun Zhang, Lei Tan, Kun Wang, Xiaobo Feng, Cao Yang, Zhiwei Liao   +21 more
wiley   +1 more source

Steroid hormone responses to three exercise modalities assessed by liquid chromatography tandem mass spectrometry in a randomized crossover trial. [PDF]

Sci Rep
McCullough D, Ferentinos P, Homer NZM, Basiukajć A, Woods DR, Gifford RM, Ispoglou T.   +6 more
europepmc   +1 more source

The VCPIP1‐UBE3A Deubiquitination‐Ubiquitination Cascade Contributes to Castration‐Resistant Prostate Cancer Progression

Advanced Science, EarlyView.
VCIPIP1 emerges as a molecular link between protein stability and prostate cancer progression. By deubiquitinating and stabilizing UBE3A, VCIPIP1 promotes p53 degradation and progression to castration‐resistant prostate cancer. Elevated VCIPIP1 expression is associated with shorter castration‐resistant prostate cancer–free survival, highlighting the ...
Fei Lin, Wen‐Cai Zheng, Yi‐Qiu Wang, Bin Lin, Yun‐Zhi Lin, Dong‐Ning Chen, Xiao‐Dong Li, Xue‐Yi Xue, Yong Wei, Ning Xu   +9 more
wiley   +1 more source

Analysis of risk factors for tic disorders in children in Hubei region based on liquid chromatography-tandem mass spectrometry. [PDF]

Front Neurosci
Hao Y, Ran R, Cheng L, Lu D.
europepmc   +1 more source

Histone Lactylation Drives WNK1 Expression to Promote Esophageal Squamous Cell Carcinoma Progression Through Histone H3 Ser10 Phosphorylation

Advanced Science, EarlyView.
In brief. Yan et al. demonstrated that the excess lactate produced by the enhanced glycolysis pathway in esophageal cancer can lactylate H3K23, H3K23la can be enriched in the WNK1 promoter region to promote WNK1 expression, thereby increasing the phosphorylation of the p‐H3 Ser10 site, and p‐H3S10 can be enriched in the AKT1 promoter region to promote ...
Mingyang Yan, Shaobo Fang, Yanming Song, Lei Zhang, Kexin Zhao, Zhenwei Wang, Yang Shao, Meng Liu, Xinyang Jia, Qinxin Guo, Mee‐Hyun Lee, Guoguo Jin, Zigang Dong   +12 more
wiley   +1 more source

Per- and Polyfluoroalkyl Substances (PFAS) in Food Products by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS), AOAC Official Method 2025.07, First Action. [PDF]

J AOAC Int
Matsubara T, Mizuno Y, Imoto E, Maeshima N, Kobayashi M, Kunihiro O, Lipps W.   +6 more
europepmc   +1 more source

BRCA1 Mutation‐Recognizing Tetrahedral Framework Nucleic Acid Nanoplatform Enables Coordinated PARP/WEE1 Inhibition and STING‐Associated Antitumor Immunity in Ovarian Cancer

Advanced Science, EarlyView.
BRCA1 mutation‐responsive FBOA‐tFNA selectively recognizes mutant transcripts and coordinates reduction‐responsive intracellular delivery of olaparib and adavosertib, amplifying DNA damage and weakening G2/M checkpoint protection. These effects are accompanied by STING‐associated immune activation and stronger antitumor immunity, while sequential anti ...
Chenyi Wang, Mengying Yao, Jinhui Xie, Dingjie Wang, Yashi Shi, Xiaodan Mao, Chunhua Lu, Pengming Sun   +7 more
wiley   +1 more source

Relationship between 25-hydroxyvitamin D by liquid chromatography-tandem mass spectrometry and retinopathy in type 2 diabetes mellitus. [PDF]

Medicine (Baltimore)
Chen S, Zheng S, Yan Y, Lin L, Zhou X, Chen N, Chen J.   +6 more
europepmc   +1 more source

Hydrodynamic Selection of Polymorphic Assembly Pathways in Plant Protein Amyloid Fibrils

Advanced Science, EarlyView.
Hydrodynamic conditions are revealed to govern polymorphic assembly of soy protein amyloid fibrils. Distinct flow‐induced drafting, kissing, and docking dynamics direct fibril growth into multiple morphologies, linking fluid mechanics with nanoscale assembly and enabling rational design of functional amyloid materials.
Zejian Xu, Pengfei Yang, Meng Li, Zichen Cao, Tian Lan, Yan Zhang, Weibiao Zhou, Lianzhou Jiang, Xiaonan Sui   +8 more
wiley   +1 more source