Results 81 to 90 of about 868,025 (315)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Light spectrum effects on micropropagation and gene expression of Bucephalandra sp. in a temporary immersion system for sustainable production

open access: yesFrontiers in Plant Science
Bucephalandra sp. ‘Wavy Dark Green’ is a commercially valuable ornamental aquatic plant with limited propagation potential due to low multiplication rates and acclimatization challenges. This study aimed to developed an integrated tissue culture protocol
Chanakan Laksana   +3 more
doaj   +1 more source

Characterization and Biocompatibility Study of Nematic and Cholesteryl Liquid Crystals.

open access: yes, 2009
NoIntensive research in bio-engineering has been conducted in the search for flexible biomaterials that could support cell growth and cells attachment.
Denyer, Morgan C.T.   +6 more
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

open access: yesMolecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy   +10 more
wiley   +1 more source

Efficiency of semi-automated culture systems on microtubers formation of yam (Dioscorea alata L.) [PDF]

open access: yesBiotechnologie, Agronomie, Société et Environnement, 2012
Yam clone 'Belep' in temporary immersion system showed favorable results on microtubers formation. Plants cultivated in this type of culture system were the first ones to initiate microtubers formation and produced the highest microtubers number per ...
Jova, MC.   +3 more
doaj  

Density control method for dense-medium suspension based on fuzzy control

open access: yesGong-kuang zidonghua, 2018
In view of problems of poor accuracy and universality of existing density fuzzy control methods for dense-medium suspension, a density control method for dense-medium suspension based on fuzzy control was proposed.
KONG Fanmiao   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Liquid-liquid Extraction of Copper(II), Cadmium(II), Lead(II) and Zinc(II) from Perchlorate and Tartrate Media by Di-2-methylnonylphosphoric Acid into Heptane [PDF]

open access: yes, 2009
The liquid-liquid extraction equilibrium of Cu(II), Cd(II), Pb(II) and Zn(II) from 0.10 M perchlorate medium by di-2-methylnonylphosphoric acid (DMNPA) as an extractant dissolved in heptane has been investigated.
XUE, Min   +2 more
core  

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