Results 111 to 120 of about 80,046 (233)

Functional Characterization of the Cat and Dog Wild‐Type and Mutant MDR1 Carrier Proteins and Frequency of the MDR1 Gene Mutation in 800 Cats From Germany

Journal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The ATP‐binding cassette transporter MDR1 P‐glycoprotein (syn. ABCB1) is an efflux carrier at the cell membrane that regulates drug absorption, distribution, and elimination. At the blood–brain barrier, MDR1 restricts brain entry of potentially neurotoxic drugs, such as ivermectin. In dogs and cats, MDR1 (syn.
Lisa Siegl, Mies Bethäuser, Daniela Nürnberger, Stefan Oswald, Andreas Moritz, Melanie Hamann, Joachim Geyer   +6 more
wiley   +1 more source

Universal use of alpha/beta mode in liquid scintillation counting analysis for both alpha/beta and single nuclide determination. [PDF]

J Radioanal Nucl Chem, 2021
Piraner O, Jones RL.
europepmc   +1 more source

Da Vinci's mischief: xylem conduits in the stems of woody plants do not furcate

New Phytologist, EarlyView.
Summary The hydraulic architecture of plants is often modeled as a ‘furcating’ network, in which xylem conduits proliferate in number toward the stem apex, analogous to animal circulatory systems. Yet whether furcation actually occurs within woody stems remains untested, despite major implications for carbon costs and hydraulic efficiency.
Gilberto Alemán‐Sancheschúlz, Tommaso Anfodillo, Ana Isabel Pérez‐Maussán, María Magdalena Ayala‐Hernández, Mark E. Olson   +4 more
wiley   +1 more source

Greater Resistance to Drought‐Induced Embolism Is Linked to Higher Yield Maintenance in Soybean

Plant, Cell &Environment, EarlyView.
ABSTRACT With increasing drought events worldwide, crop breeding must focus on drought resistance to maintain crop yields. To ensure a high level of gas exchange and growth, plants need to maintain the integrity of their vascular system under drought conditions. While the impact of drought‐induced vascular damage on tree species is well‐documented, its
Viviane Schell, Léa Kervroëdan, Déborah Corso, Daniela Yipenin N'do, Michel‐Pierre Faucon, Sylvain Delzon   +5 more
wiley   +1 more source

Distinct Foliar Uptake Pathways for Phosphorus and Nano‐Hydroxyapatite in Potato Revealed By Synchrotron μCT and ³³P Imaging

Plant, Cell &Environment, EarlyView.
ABSTRACT Potato (Solanum tuberosum L.) has a high phosphorus (P) requirement, yet its shallow root system and the strong P‐fixing capacity of many soils limit the effectiveness of soil fertilisation. Foliar application of nano‐hydroxyapatite particles (nHAPs) has emerged as a promising alternative P fertilisation practice.
Max Frank, Stine Le Tougaard, Augusta Szameitat, Emil Visby Kristensen, Daniel P. Persson, Rajmund Mokso, Søren Husted   +6 more
wiley   +1 more source

Unveiling protective mechanisms of wild olive (acebuche) oil in retinal pigment epithelial cells with hypertensive phenotype

The Journal of Physiology, EarlyView.
Abstract figure legend Circulating extracellular vesicles (EVs) derived from acebuche (ACE) oil‐ and extra virgin olive oil (EVOO)‐fed mice modulate nitric oxide (NO) metabolism in the retinal pigment epithelial cell line (ARPE19) with a hypertensive phenotype induced by angiotensin II (AngII).
Álvaro Santana‐Garrido, Claudia Reyes‐Goya, Pablo Espinosa‐Martín, Rosa M. Troya‐Toledo, Helder André, Alfonso Mate, Carmen M. Vázquez   +6 more
wiley   +1 more source

The research program of the Liquid Scintillation Detector (LSD) in the Mont Blanc Laboratory [PDF]

A massive (90 tons) liquid scintillation detector (LSD) has been running since October 1984 in the Mont Blanc Laboratory at a depth of 5,200 hg/sq cm of standard rock.
Badino, G., Dadykin, V. L., Korchagin, P. V., Korchagin, V. B., Malgin, A. S., Ryassny, F. G., Ryazhskaya, O. G., Talochkin, V. P., Yakushev, V. F., Zatsepin, G. T.   +9 more
core   +1 more source

MCT1‐mediated bidirectional propionate transport across human placental syncytiotrophoblast layer: insights from a trophoblast stem cell‐derived barrier model

The Journal of Physiology, EarlyView.
Abstract figure legend Propionate in the fetal circulation is thought to originate from fermentation of dietary fibre by the maternal gut microbiota. However, the mechanism of transplacental transport has remained unclear. Here, we measured propionate permeability using a placental barrier model generated by differentiating human placental trophoblast ...
Toshiaki Tsuchitani, Rin Midorikawa, Akari Kasuya, Saki Noguchi, Kohei Yamamoto, Tomohiro Nishimura, Hirokazu Kaji, Takeshi Hori, Masatoshi Tomi   +8 more
wiley   +1 more source

Transfer of paracetamol across the placenta and fetal blood–brain barriers and its safety for use in pregnancy

The Journal of Physiology, EarlyView.
Abstract figure legend Paracetamol (acetaminophen) is commonly taken during pregnancy for pain and fever. To gain a more comprehensive understanding of paracetamol's effects during pregnancy, several elements need to be examined including the transfer of paracetamol across the placenta and into the developing brain, the short‐ and long‐term effects of ...
Yifan Huang, Liam Koehn
wiley   +1 more source

Net mineralizable soil phosphorus cannot be measured by non‐isotopic approaches

Agricultural &Environmental Letters, Volume 11, Issue 1, June 2026.
Abstract While radioisotopic pool dilution is widely regarded as the most reliable method for estimating soil phosphorus mineralization (Pmin), high costs, low throughput, and safety requirements limit its use. We evaluated the potential of non‐radioisotopic approaches to estimating net Pmin by difference before and after aerobic incubation, analogous ...
Chongyang Li, Andrew J. Margenot
wiley   +1 more source