Results 151 to 160 of about 83,550 (282)

Biochemical Characterization of an Atypical Variant Flanking or Affecting the Initiation or Start Methionine Codon in CHST14 in a Patient With Musculocontractural Ehlers–Danlos Syndrome

Proteoglycan Research, Volume 4, Issue 1, January 2026.
ABSTRACT Musculocontractural Ehlers‐Danlos syndrome (EDS) caused by pathogenic variants in the carbohydrate sulfotransferase 14 gene (CHST14) (mcEDS‐CHST14) is an autosomal recessive connective tissue disorder characterized by congenital malformations including specific craniofacial features, congenital multiple contractures, and progressive fragility ...
Shuji Mizumoto, Tomoki Kosho, Tomoko Honda, Atsushi Hatamochi, Kazuyuki Sugahara, Naomichi Matsumoto, Noriko Miyake, Shuhei Yamada   +7 more
wiley   +1 more source

Activity‐restoring mutations in the histamine H3 receptor increase constitutive activity and reduce structural stability

Protein Science, Volume 35, Issue 1, January 2026.
Abstract The histamine H3 receptor (H3R) is a class A G protein‐coupled receptor (GPCR) that regulates neurotransmitter release in the central nervous system. Although structures of H3R in both inactive and active states have been elucidated, the functional roles of specific residues remain unclear.
Ami Nakajima, Hiroto Kaneko, Kosuke Oyama, Misumi Kuchiji, Ayane Itakura, Chiaki Arai, Mitsunori Shiroishi   +6 more
wiley   +1 more source

Defining substrate specificities of human RNA capping methyltransferases through quantitative assessment of independent yet cooperative activities

Protein Science, Volume 35, Issue 1, January 2026.
Abstract Human RNA capping is critical for mRNA splicing, protection of RNA from 5′ exonucleases in the cytoplasm, and targeting to the ribosome. Human RNMT, CMTR1, and CMTR2 are RNA methyltransferases involved in the RNA capping process. They play a significant role in the proliferation and differentiation of embryonic stem cells and have been ...
Fatemeh Taherian, Mark F. Mabanglo, Taraneh Hajian, Sarah Tucker, Emilija Kalinic, Sumera Perveen, Ahmed Aman, Masoud Vedadi   +7 more
wiley   +1 more source

Method for Determination of 55Fe in Radioactive Used Oil from Nuclear Power Plant

Yuanzineng kexue jishu
55Fe is an important corresponding activation product during the operation of nuclear power plants. 55Fe may be present in the used oil required for main circuit mechanical equipment through cross-contaminating during maintenance activities-including ...
MA Lina1, 2, FAN Fuyou3, QIU Xiangping3, WANG Lusheng1, 2, DAI Xiongxin1, 2
doaj   +1 more source

Use of Plastic Mini-Vial on On-Line Computerized Liquid Scintillation System for 3H and 14C Counting

, 1975
Mitsuyoshi Matsuo, Keiko Ono, Takao Kaneko, Jun Kikuchi   +3 more
openalex   +2 more sources

High-efficiency liquid-scintillation counting of 14C-labelled material in aqueous solution and determination of specific activity of labelled proteins [PDF]

, 1965
TC Hall, EC Cocking
openalex   +1 more source

Synchrotron structural biology at SSRL, the beginning and beyond

Journal of Synchrotron Radiation, Volume 33, Issue 1, Page 7-17, January 2026.
It has been 50 years since the publication in PNAS of our first results on the utilization and demonstrated benefits of synchrotron radiation for macromolecular crystallography. In this brief article, I offer some personal observations and comments about that early research at Stanford and the Stanford Synchrotron Radiation Project (SSRP, later renamed
Keith Hodgson
wiley   +1 more source

Solid scintillator "Ready Cap" for measurement with a liquid scintillation counter. Spectra and counting efficiencies for 15 different radionuclides.

, 1990
Kenichi Ijiri, Masashi Endo, Susumu Osaki, Norio Nogawa, Shoko TSUDA, Aiko NAKAMURA, Naotake MORIKAWA   +6 more
openalex   +2 more sources

Liquid scintillation counting can underestimate 14C-activity of 14CO2 trapped in NaOH

, 2022
Elinor F. Boos, Jakob Magid, Sander Bruun, Niels O. G. Jørgensen   +3 more
openalex   +1 more source

Increased ATP production and P‐glycoprotein activity underlie the marked changes in blood–brain barrier transport of drugs in a mouse model of amyotrophic lateral sclerosis

British Journal of Pharmacology, Volume 183, Issue 2, Page 280-295, January 2026.
Background and purpose Patients with amyotrophic lateral sclerosis (ALS) are prescribed many medications for symptomatic relief. However, how potential alterations to the blood–brain barrier (BBB) affect the brain exposure of drugs in ALS remains under‐investigated. Experimental approach We used high‐dimensional proteomic analysis, cellular metabolism,
Yijun Pan, Alanna G. Spiteri, Pranav Runwal, Jiaqi Sun, Dana S. Hutchinson, Yoshiteru Kagawa, Bradley J. Turner, Cheng Huang, Anup D. Shah, Ralf B. Schittenhelm, Joseph A. Nicolazzo   +10 more
wiley   +1 more source