Results 91 to 100 of about 1,800,591 (295)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Liquidity Shortages and Banking Crises [PDF]

Banks can fail either because they are insolvent or because an aggregate shortage of liquidity can render them insolvent. We show that bank failures can themselves cause liquidity shortages.
Raghuram G. Rajan, Douglas W. Diamond
core  

Assessing the impact of liquidity creation, ESG performance, and ESG regulation on banking stability

Cogent Economics & Finance
This study examines the relationship between banks’ liquidity creation and banking stability using a two-step System GMM approach on a global bank panel (2014–2023), distinguishing between Advanced Economies (AEs) and Emerging Market and Developing ...
Rendy Pradana Hamidjaya, Dwi Nastiti Danarsari   +1 more
doaj   +1 more source

International monetary reform and the less developed countries

PSL Quarterly Review, 2014
The present article discusses the implications of international monetary reform for the development of the less developed countries (LDCs). The author first considers liquidity and the proposal for a “link” between monetary reform and the provision of ...
P. STREETEN
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

CARMEL liquidity indicators of insurance companies [PDF]

Ekonomija: teorija i praksa, 2018
The adoption of guidelines by the National Bank of Serbia in the field of insurance enabled the creation of conditions for a safe and stable insurance market.
Milić Dragana, Matijašević-Obradović Jelena   +1 more
doaj  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Liquidity Creation and Bank Capital [PDF]

, 2019
This paper aims to evaluate the relationship between capital and liquidity following the implementation of the Basel III rules. These regulatory measures target both increased capital ratios and a reduction of banks’ maturity transformation risk , which ...
di Pietro, F., Casu, B., Trujillo-Ponce, A.   +2 more
core   +1 more source

Digital Transformation and Bank Liquidity Creation: Evidence From a Bank-Based Market

SAGE Open
This study explores how digital transformation influences the ability of Vietnamese commercial banks to generate liquidity, utilizing panel data from 2007 to 2022.
Japan Huynh
doaj   +1 more source

Carbon information disclosure of enterprises and their value creation through market liquidity and cost of equity capital

Journal of Industrial Engineering and Management, 2015
Purpose: Drawing on asymmetric information and stakeholder theories, this paper investigates two mechanisms, namely market liquidity and cost of equity capital, by which the carbon information disclosure of enterprises can benefit their value creation ...
Li Li, Yuanhua Yang, Dengli Tang
doaj   +1 more source