Results 131 to 140 of about 11,613 (304)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

The Index Effect: An Investigation of the Price, Volume and Trading Effects Surrounding Changes to the S & P Australian Indices [PDF]

open access: yes
This paper examines the stock price and volume effects surrounding the announcement of constituent changes to the S&P/ASX 200 and four supplementary indices.
Daniel Pullen, Gerard Gannon
core  

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Flight to Liquidity and Global Equity Returns

open access: yes
Investment practice and academic literature suggest a great degree of interaction between the world’s stock markets and most liquid and safe assets, such as U.S. Treasuries.
Goyenko, Ruslan, Sarkissian, Sergei
core  

LIQUIDITY MANAGEMENT AND CORPORATE RISK [PDF]

open access: yes
The consequence of the economic crisis, the access of the external financing resources was narrowed significantly and lenders had became more cautious. This meant that the external source providers analyze more thoroughly the source claimants, and they ...
Tarnoczi Tibor, Fenyves Veronika
core  

Voluntary Disclosure and Liquidity: Evidence from Index Funds. [PDF]

open access: yes, 2015
Index funds trade for nonstrategic reasons because their clients’ personal liquidity needs primarily drive fund flows. These funds are thus unambiguously more likely than strategic traders to prefer high stock liquidity, and thus high disclosure, to ...
Schoenfeld, Jordan Mychael
core  

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

open access: yesFEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart   +7 more
wiley   +1 more source

Refractive Index of Different Liquids

open access: yes
This project studies how light bends in different liquids such as glycerin, oil and acetone. Using a convex lens and optical tools, the refractive indices were calculated, showing that each liquid changes the path of light differently. The work highlights key concepts of optics and provides practical experimental insights.
openaire   +2 more sources

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

open access: yesFEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda   +12 more
wiley   +1 more source

Liquidity Effects of Changes in a Pan-European Stock Index [PDF]

open access: yes
Adding or deleting a security to or from an index can influence the share price considerably. A possible explanation that has been brought forward in the literature is the liquidity hypothesis according to which an increase in liquidity after an addition
Ulrich Pape, Stephan Schmidt-Tank
core  

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