Results 31 to 40 of about 25,739 (194)

Anti-inflammatory activity of lisinopril in albino rats

National Journal of Physiology, Pharmacy and Pharmacology, 2018
Background: Angiotensin II (Ang II) is a product of renin angiotensin aldosterone system. Angiotensin‑II regulates vascular tone, stimulates the release of pro‑inflammatory cytokines, activates nuclear factor‑kappa B, increases oxidant ...
Siddamma Amoghimath, Suresha R N
doaj   +1 more source

DEVELOPMENT OF METHODS OF SIMULATION OF THE INTERACTION OF BIOLOGICALLY ACTIVE SUBSTANCES WITH THE ACTIVE CENTER OF ANGIOTENSIN-CONVERTING ENZYME

Фармация и фармакология (Пятигорск), 2017
Nowadays cardiovascular diseases are the main cause of death among the population around the word. The development of new drugs, giving a possibility to normalize blood pressure, is a promising direction in the field of pharmacy and medicine.
A. A. Glushko, A. S. Chiriapkin, V. S. Chiriapkin, A. M. Murtuzalieva, Yu. A. Polkovnikova   +4 more
doaj   +1 more source

Regulation of the renal angiotensin II receptor gene in acute unilateral ureteral obstruction [PDF]

, 1994
Regulation of the renal angiotensin II receptor gene in acute unilateral ureteral obstruction. We have shown that acute (24-hr) unilateral ureteral obstruction (UUO) induces the genes encoding for renin, in juxtaglomerular apparatuses and in tubules, for
Pimentel, J. Luis, Wang, Susheng, Martinez-Maldonado, Manuel   +2 more
core   +1 more source

CARDIOPROTECTIVE PROPERTIES OF LISINOPRIL: NEW POSSIBILITIES

Рациональная фармакотерапия в кардиологии, 2018
Aim. To study the changes in the stiffness of the arterial wall, vasomotor function of the endothelium, and appearance of new cases of atrial fibrillation (AF) in patients with arterial hypertension with long-term treatment with lisinopril.Material and ...
V. I. Podzolkov, A. I. Tarzimanova, R. G. Gataulin   +2 more
doaj   +1 more source

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Risiko Penggunaan ACEi Terhadap Kejadian Batuk Kering Pada Pasien Hipertensi Di RSUD Cengkareng Dan RSUD Tarakan DKI Jakarta [PDF]

, 2015
The use of angiotensin converting enzyme inhibitors (ACEi) as an antihypertensive agent can cause side effects such as dry cough. The aim of this study is to evaluate risk of ACEi administration on dry cough incidence with captopril as the standard ...
Andrajati, R. (Retnosari), Halim, M. C. (Margareth), Supardi, S. (Sudibyo)   +2 more
core   +3 more sources

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

British Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić, Marta Kučan Štiglić, Ana Jelaković, Bojan Jelaković, Dinko Vitezić   +4 more
wiley   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

ESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo, Tor Biering‐Sorensen, Joao P. Ferreira, Carlo Mario Lombardi, Andrea Bonelli, Andrea Garascia, Marco Metra, Riccardo M. Inciardi   +7 more
wiley   +1 more source

Sang-Yod rice bran hydrolysates alleviate hypertension, endothelial dysfunction, vascular remodeling, and oxidative stress in nitric oxide deficient hypertensive rats

Asian Pacific Journal of Tropical Biomedicine, 2021
Objective: To evaluate the potential therapeutic effect of Sang-Yod rice bran hydrolysates (SRH) and in combination with lisinopril against hypertension, endothelial dysfunction, vascular remodeling, and oxidative stress in rats with nitric oxide ...
Gulladawan Jan-On, Akarachai Tubsakul, Weerapon Sangartit, Poungrat Pakdeechote, Veerapol Kukongviriyapan, Ketmanee Senaphan, Chakree Thongraung, Upa Kukongviriyapan   +7 more
doaj   +1 more source

Pengaruh Pelarut terhadap Optimasi Reaksi Derivatisasi Lisinopril dengan 1-Fluoro-2,4-Dinitrobenzene serta Pemilihan Standar Internalnya [PDF]

, 2016
Telah dilakukan penelitian untuk mengoptimasi reaksi derivatisasi lisinopril dalam pelarut aquades dan metanol dengan 1-fluoro-2,4-dinitrobenzene (FDNB) serta memilih standard internal.
., Sugiyanto, Martono, Sudibyo, Sumiyani, Ririn   +2 more
core