Results 51 to 60 of about 2,673,660 (285)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Texas Adopted Textbook List 1995 [PDF]

open access: yes, 1995
List of textbooks adopted by the State of Texas for use in K-12 public schools.UT ...
Texas State Department of Education
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Estimation of the Number of Volatile Compounds in Simple Mixtures

open access: yesProceedings, 2017
In this paper, we address the problem of simple mixtures identification using a SAW sensor based e-nose. First, we propose a linearized form of the SAW sensor’s response to mixtures.
Olivier Hotel   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Der Pazifische Raum [cartographic material].

open access: yes, 1942
Map of the Pacific Rim Region showing railways and shipping routes.; Prime meridian: Greenwich.; On verso: Best.-Nr. 029.; In lower left margin: 10.4.42.; In upper right margin: Korrektur 9.4.42.; Includes shipping route distances.; Also available online
List & von Bressensdorf.
core  

Texas Adoption Textbook List 2021

open access: yes, 2021
List of textbooks adopted by the State of Texas for use in K-12 public schools.UT ...
Texas State Department of Education
core   +1 more source

Morfofiziološki pokazatelji analize podmlatka bukve Fagus silvatica L. u uslovima Š.U. Podgradci

open access: yesGlasnik Šumarskog Fakulteta Univerziteta u Banjoj Luci, 2009
Cilј rada je da se utvrdi stanje podmlatka bukve u uslovima rasta i razvića u rejonu planine Prosare. Poznavanje stanja i brzine rasta šumskog podmlatka važan je pokazatelј koji govori o mogućnosti podmlatka određene vrste da se izbori u prvim godinama ...
Rodoljub Oljača   +3 more
doaj  

A Generic Friction Model for Radial Slider Bearing Simulation Considering Elastic and Plastic Deformation

open access: yesLubricants, 2015
The investigation of component dynamics is one of the main tasks of internal combustion engine (ICE) simulation. This prediction is important in order to understand complex loading conditions, which happen in a running ICE.
Günter Offner, Oliver Knaus
doaj   +1 more source

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