Results 111 to 120 of about 115,985 (312)

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Choice Numbers of Chordal, Chordless, and Some Non-Chordal Graphs

open access: yesMathematics
We prove that chordal graphs are chromatic-choosable and present a decomposition theorem to help estimate the choice numbers for certain classes of chordless and non-chordal graphs.
Julian Allagan   +3 more
doaj   +1 more source

Colorings v.s. list colorings of uniform hypergraphs

open access: yes, 2018
Let $r$ be an integer with $r\ge 2$ and $G$ be a connected $r$-uniform hypergraph with $m$ edges. By refining the broken cycle theorem for hypergraphs, we show that if $k>\frac{m-1}{\ln(1+\sqrt{2})}\approx 1.135 (m-1)$ then the $k$-list assignment of $G$ admitting the fewest colorings is the constant list assignment.
Wang, Wei, Qian, Jianguo, Yan, Zhidan
openaire   +2 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Stationary list colorings

open access: yes
Komjath studied the list chromatic number of infinite graphs and introduced the notion of restricted list chromatic number. For a graph $X=(V_X,E_X)$ and a cardinal $κ$, we say that $X$ is restricted list colorable for $κ$ if for every $L:V_X\to[κ]^κ$ there is a choice function $c$ of $L$ such that $c(v)\neq c(w)$ whenever ${v,w}\in E_X$. In this paper,
openaire   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

List strong edge-coloring of graphs with maximum degree 4 [PDF]

open access: green, 2018
Baochen Zhang   +4 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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