Results 171 to 180 of about 2,130,929 (294)

SEC Mediates m6A Deposition and Transcription Pause Release to Drive Cell Identity Transition

Advanced Science, EarlyView.
The SEC promotes cell identity transitions by facilitating transcription pause release at key identity‐associated genes, including Klf4 and Myc during iPSC reprogramming and Nes and Tubb3 during ESC‐to‐neuroectodermal differentiation. During early iPSC reprogramming, this function additionally involves cooperation with METTL3‐associated m6A regulation.
Zhijing Zhang, Jingyi Xu, Yonghong Wu, Yitong Qu, Xinglin Hu, Yuchen Sun, Yanshuang Wu, Zhonghua Liu, Jiaqiang Wang, Lei Lei   +9 more
wiley   +1 more source

Configuration analysis on servitisation transformation of sporting goods manufacturing enterprises: The case study of 33 listed companies of China. [PDF]

PLoS One
Hu Y, Lu L, Li Q.
europepmc   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

An exploratory study on the impact of ESG on business performance-Focusing on listed companies in Korea and Taiwan. [PDF]

PLoS One
Fan S.
europepmc   +1 more source

FAK Mediated Coordination of Extracellular Matrix Remodeling and Cellular Mechanics Impairs Nanomedicine Delivery in Solid Tumors

Advanced Science, EarlyView.
FAK orchestrates a mechanical barrier limiting nanomedicine accumulation in solid tumors by coupling ECM remodeling with cytoskeletal tension. Genetic or pharmacological FAK inhibition dismantles this barrier, enhances clathrin‐mediated uptake and penetration, and overcomes delivery limitations to improve antitumor efficacy.
Tian Zhao, Hao Wu, Yujie Qin, Jingfei Zhu, Ye Huang, Wei Chen, Jiaxuan Yu, Xiang Qin, Shun Li, Junjie Li, Tingting Li, Yiyao Liu   +11 more
wiley   +1 more source

Research on credit risk of listed companies: a hybrid model based on TCN and DilateFormer. [PDF]

Sci Rep
Shen C, Wu J.
europepmc   +1 more source

A Biomimetic Solvatochromic Chip With Optimized Chemical Diversity for On‐Site Liquid Identification

Advanced Science, EarlyView.
A compact biomimetic photonic‐gustatory chip uses Hansen‐solubility‐parameter‐guided solvatochromic disks to create distinct color patterns in organic liquids. An optimized four‐disk array distinguishes solvent types, ratios, homologues, isomers, and alcoholic beverages. Coupled with smartphone imaging and deep learning, it identifies 80 liquid classes
Jintao Zhang, Hao Ouyang, Yin Cheng, Nuoye Xiong, Xunchi Ma, Xueling Li, Guangming Zhu, Liang Zhang, Jing Sun, Ranran Wang   +9 more
wiley   +1 more source

The impact of China's low-carbon policies' intensity on the labor demand of listed companies. [PDF]

Heliyon
Gao Y, Guan X.
europepmc   +1 more source

Dual‐Functional Membranes With Interfacial MXene/PFSA Nanoarchitectures for Low Hydrogen Permeation in Water Electrolysis and Reduced Vanadium Ion Crossover in Flow Batteries

Advanced Science, EarlyView.
A PFSA/MXene composite membrane is developed for both PEMWE and VRFB applications. MXene incorporation simultaneously enhances proton conductivity and suppresses hydrogen/vanadium crossover. The interaction between MXene functional groups and PFSA's –SO3H reduces the proton diffusion barrier via hydrogen‐bonding networks, while the disordered ...
Panpan Guan, Mingjia Jiang, Yunhu Jiang, Wei Li, Yecheng Zou, Lixiao Zhang, Kaifeng Long, Ziqi Sun, Ting Liao, Hua Kun Liu, Ding Yuan, Dingsheng Wang, Shi Xue Dou, Yuhai Dou   +13 more
wiley   +1 more source

Financial assessment and diagnosis of abnormal data of listed companies in public health and wellness industry. [PDF]

Front Public Health
Liu X, Li Y, Zhang S.
europepmc   +1 more source