Results 131 to 140 of about 151,604 (360)

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

He Said, She Said: A Feminist Approach to Teaching the Twentieth-Century Novel in the Twenty-First Century

, 2000
The question of women\u27s relationship to the literary canon is still pertinent today and is particularly significant for those of us who are both guided by feminist pedagogy and constrained by departmental limitations. How do we give an overview of the
Viti, Elizabeth Richardson
core  

Editorialising practices, competitive marketablility and James Thomson's 'The seasons' [PDF]

, 2015
The lapse of Andrew Millar's copyright for James Thomson's The Seasons in 1765 resulted in an increasing number of new editions of the poem being published in the late eighteenth century.
Van De Walle, Kwinten
core  

“Russian author” in 1739: Gottlieb Bayer, Ivan Taubert and the First Steps of Russian School Literary Canon

, 2019
Andrei A. Kostin, Tatiana Kostina
openalex   +1 more source

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Przekłady literatury polskiej na język francuski jako próba ustalania kanonu – reinterpretacja i reintegracja w systemie literackiej kultury francuskiej

Postscriptum Polonistyczne, 2020
The author poses the question whether Polish literary canon that has been established since Romanticism through translations into French can be used in the joint­‑creation of the canon of European literature.
Jadwiga Warchoł
doaj  

The democratical ideal and the Oresteia between 'Back to Basics' and cultural studies, between old and new historicism [PDF]

, 2004
A
Decreus, Freddy
core   +1 more source

Potent and Long‐Lasting Immunogenicity Generated by LNP‐mRNA gE Antigen Against Varicella Zoster Virus via an AI‐Assisted Pipeline

Advanced Science, EarlyView.
This study designs a novel mRNA‐LNP vaccine targeting VZV glycoprotein E (gE) for herpes zoster via an AI‐assisted pipeline. Validated in mice and rhesus macaques, the mRNA‐LNP vaccine shows strong humoral and cellular immune responses, with CD4+ T‐cell responses more effective and durable than Shingrix, offering a promising prophylactic option ...
Kai Dong, Fang Liu, Dawei Wang, Yanfen Li, Man Zhang, Yuting Zhou, Gengshen Song   +6 more
wiley   +1 more source

Timekeeper Outside the Canon: Roksanda Njeguš’s Prose in the Serbian Literary System [PDF]

Дарко Илин
openalex   +1 more source