Results 181 to 190 of about 151,604 (360)

Parallel Genome‐Wide CRISPR Screens Reveal SORL1 and ZFYVE19 as Sequential Host Determinants of Salmonella Infection

Advanced Science, EarlyView.
To distinguish how Salmonella invades cells vs how it survives long‐term, a parallel CRISPR screening platform is developed. This approach reveals the host proteins that the bacterium exploits at different stages of infection. The study identifies SORL1 as a novel host factor for invasion and demonstrates that blocking it with an antibody effectively ...
Sehee Yun, Seoyeon Kim, Seonggyu Kim, Minsoo Noh, Dae‐Kyum Kim, Eun‐Jin Lee, Hunsang Lee   +6 more
wiley   +1 more source

The Stethoscope Song: A Professional Ballad by One of America's Earliest Physician-Writers. [PDF]

Methodist Debakey Cardiovasc J
Cordova JC, Young JB.
europepmc   +1 more source

Representation of autism in fictional media: A systematic review of media content and its impact on viewer knowledge and understanding of autism. [PDF]

Autism, 2023
Jones SC, Gordon CS, Mizzi S.
europepmc   +1 more source

Targeting Microglial CD49a Inhibits Neuroinflammation and Demonstrates Therapeutic Potential for Parkinson's Disease

Advanced Science, EarlyView.
This study shows that integrin receptor CD49a (Itga1 gene) is significantly upregulated in hyperactivated microglia and microglia‐specific knockdown of Itga1 rescues neuroinflammation and neurodegeneration in a chronic Parkinson's disease (PD) model by targeting PGAM5‐mediated mitochondrial dysfunction and NLRP3 activation. Targeted inhibition of CD49a
Huanpeng Lu, Yunmin Zhu, Xi Wang, Zelin Wu, Zijian Xu, Rongqing Chen, Yanwu Guo   +6 more
wiley   +1 more source

First as a Tragedy, Then as some Other Figure: On Tropology of History and Politics of Literature. [PDF]

Open Res Eur
Glavaš Z.
europepmc   +1 more source

AN APOLOGY OF THE LITERARY CANON IN A LINGUISTIC STUDY

, 2015
А. В. Соснин
openalex   +2 more sources

Decoding Triphenotypic Neutrophils in Cervical Cancer Evolution and Targeting SPP1+/GBP1+/ELOVL5+ Tumor‐Associated Neutrophils to Sensitize Immunotherapy

Advanced Science, EarlyView.
The functional schematic diagram of tumor associated neutrophils. Abstract Enhancing cervical cancer (CC) immunotherapy requires deciphering the heterogeneous tumor immune microenvironment (TIME), particularly neutrophil phenotypic dynamics. Here, 1) we collected 543 CC cases to find that patients with elevated neutrophil levels have a higher incidence
Xingyu Chang, Xinyu Qu, Tingting Ren, Tong Wu, Weiyong Gu, Jingxin Ding, Keqin Hua, Junjun Qiu   +7 more
wiley   +1 more source

A Scottish National Canon? Process of Literary Canon Formation in Scotland

Miscelánea: A Journal of English and American Studies, 2014
Jessica Aliaga Lavrijsen
doaj   +1 more source

Spectral interlocutions and the politics of unfinished: Buddhism, haunting, and memory in Karunatilaka's <i>The Seven Moons of Maali Almeida</i>. [PDF]

Front Sociol
Humphry NM, I A.
europepmc   +1 more source

Inclusions and exclusions. [PDF]

Lat Stud, 2020
Torres L.
europepmc   +1 more source