Results 211 to 220 of about 2,728 (287)
Objective Biomarkers of disease pathogenesis are critically needed for amyotrophic lateral sclerosis (ALS) to facilitate diagnosis and patient stratification into appropriate therapeutic trials. Proteomic studies offer significant potential to advance this, but reproducibility across laboratories is a key component toward identifying protein changes ...
Gabrielle L. Adler+2 more
wiley +1 more source
Mitochondria‐targeting water‐soluble probe mTAP exclusively reacts with mitochondrial abasic sites, enabling the manipulation of mitochondrial DNA levels under genotoxic stress. Abstract Mitochondrial DNA (mtDNA) encodes essential genes for mitochondrial and cellular functions and acts as a cell signaling molecule in innate immune and inflammatory ...
Anal Jana, Yu‐Hsuan Chen, Linlin Zhao
wiley +2 more sources
The impact of school-based creative bibliotherapy interventions on child and adolescent mental health: a systematic review and realist synthesis protocol. [PDF]
Redman H+3 more
europepmc +1 more source
Mapping Postictal Aphasia through Signal Complexity: A Stereo‐Electroencephalography Study
Objective The postictal period provides an opportunity to investigate the pathophysiology underlying aphasia and recovery following epileptic seizures. This study examines postictal aphasia in stereo‐electroencephalography (SEEG)‐explored patients to identify brain regions associated with task‐specific language deficits using signal complexity analysis.
Ionuț‐Flavius Bratu+6 more
wiley +1 more source
Structural Basis for a Scaffolding Role of the COM Domain in Nonribosomal Peptide Synthetases
COM domains are known as docking domains between subunits of nonribosomal peptide synthetases (NRPSs). Here, the first structure of a fused, internal COM domain with its neighboring domains is reported. Structural, biochemical and crosslinking data show that COM domains play an unexpected role in properly positioning epimerization (E) and condensation (
Julia Diecker+7 more
wiley +2 more sources
Retranslation as a Social Activity: The Case of Chinese Literary Canon Xi You Ji
Tong Ruolin
openalex +1 more source
Read like a man: comparing narratives of masculinity in adolescent literature. [PDF]
Hernandez F, Macaluso M.
europepmc +1 more source
Applications of the Dressing Field Method are reviewed and further expanded to the very foundations of the supersymmetric framework, where it allows to build relational supersymmetric field theory. Furthermore, a novel approach is proposed giving a unified description of fermionic matter fields and bosonic gauge fields: a Matter‐Interaction ...
Jordan François, L. Ravera
wiley +1 more source
Structural shaping of a highly reactive chiral Mn‐oxo species translates into exceptionally enantioselective C─H oxidation catalyst of cyclohexyl 1,3‐meso diethers (up to >99% ee) leading to polyfunctionalized cyclohexanes. Abstract Chiral polyoxygenated cyclohexanes are valuable constituents of biologically relevant products.
Andrea Palone+7 more
wiley +2 more sources