Results 251 to 260 of about 731,688 (334)

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

open access: yesAdvanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng   +4 more
wiley   +1 more source

Is "pre-sepsis" the new sepsis? A narrative review. [PDF]

open access: yesPLoS Pathog
Gerard R   +6 more
europepmc   +1 more source

Initiating your coronation.

open access: yesAm J Physiol Heart Circ Physiol
Woods L, Robinson DL.
europepmc   +1 more source

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