Results 91 to 100 of about 3,319,950 (298)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Rushlight: The Literary Supplement [1928?]

open access: yes, 1928
Wheaton College (Norton, MA) student literary magazine.The Old Barnacle ClubSong of a Thousand Valentines"The Reconciliation"The Reformation of Louise: A story with a moralAssault and BatteryAn AppealThe Keeper of The BookshopOver the WallForegin Gods ...
Adah Hatch   +10 more
core  

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The Evolution of the Literary Neo-Hasid

open access: yes, 2011
Depictions of Hasidim changed drastically around the turn of the century in Yiddish literature. This thesis tracks this change from the early Haskalah until the Holocaust. In general, depictions of the Hasid in the nineteenth century tended to be quite negative; however, the first chapter will establish a counter-narrative of maskilim who defended ...
openaire   +2 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Forms of address in russian literary works of epistolary genre

open access: yesRussian Language Studies, 2013
Evolution and functioning of etiquette forms of address on the example of Russian literary works, written in epistolary genre is considered in the article. Literary works from various periods are taken for the analysis.
N V Ryzhova, K Y Dyakova
doaj  

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Literary Acoustics [PDF]

open access: yes, 2015
Bringing together sound studies and intermediality theory, this essay revisits the notion of ‘literary acoustics’ to inquire into the usefulness of intermediality studies for analyzing the relations between literature and sound.
Schweighauser, Philipp   +1 more
core   +1 more source

Approaches and Methods of Periodization in Literary History [PDF]

open access: yesLiterary Arts, 2013
One of the most fundamental acts of historiography is to classify historical information in diachronic axis. The method of this classification or periodization shows the theoretical approach of the historian and determines the structure and the form of ...
Naser Gholi Sarli
doaj   +2 more sources

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

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