Results 121 to 130 of about 3,319,950 (298)

Rushlight: Volume IX, November 1946

, 1946
Wheaton College (Norton, MA) student literary magazine.It's Baseball Season AgainPoemIn Defense of Jane AustenThe Tale of Mendel's GrawMidsummer LamentWish I MayThe ProphetWinter GullMemories of a MidgetNight FlightSmoke RingsTransportation Sounds in a A
Lousie Taylor, Ann Burchard, Roslyn Roth, Madeline Bourde, Patricia Wilder, Jane Hering, Amelie Banov, Patricia Colvin, Angela Schimmenti   +8 more
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Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Preferring ‘dirty’ to ‘literary’ journalism: in Australia, Margaret Simons challenges the jargon while producing the texts

, 2015
Australian literary journalism has neither a discrete nor recognisable community of authors as compared to the United States and the United Kingdom. In Australia, writers in the field do not label themselves as such and indeed, most are surprised when it
Joseph, SA
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Subject position in the diachrony of French, nominal and pronominal subjects across genres

Isogloss
This contribution analyses subject inversion in Old and Middle French (13th - 16th c.), to investigate the key steps in the loss of Verb Second grammar (V2) through time.
Francesco Pinzin, Mathieu Goux
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Transactions of the Manchester Literary Club.

, 1875
Mode of access ...
Manchester Literary Club.
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Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Rushlight: Volume XL, June 1895, No.3

, 1895
Wheaton College (Norton, MA) student literary magazine.SonnetLetter FromExtracts from the Canadian PressResolutionsAnnual Report of the New England Wheaton Seminary ClubMeetings of the New England Wheaton Seminary ClubMeetins of the New York Wheaton ...
Elizabeth B. Sharp, C.M.P, Sarah C. Scott, Jessie Maverick, Mabel Hayward Perry, Edith White, E.C (Eleanor C.) Coleman, Kate Upson Clark, Frances E. Willard, Mary Pepperrell Frost, Jeannie Woodbury Lincoln, Edith M. Thomas, Elvira S. Annan, Edith F. Mears, Annie A. Emerson   +14 more
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Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source