Results 81 to 90 of about 836,141 (310)

PARALLELED CHARACTERS IN THE DRAMATIC WORKS OF HORTENSIA PAPADAT-BENGESCU [PDF]

open access: yesDiversitate si Identitate Culturala in Europa, 2015
This article proposes a psychoanalytical approach to two paralleled literary characters whom Hortensia Papadat-Bengescu places into opposition in order to introduce her readers to feminine hypostases of wish fulfilment.
Simona GALAŢCHI
doaj  

Biography and Social History: An Intimate Relationship [PDF]

open access: yes, 2004
Biography has been considered as outside the discipline of history by many historians. Since the chronological framework of the study is pre-deter-mined, given the subject\u27s life, it has been argued, it does not meet the fundamental historical test of
Salvatore, Nick
core   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Towards a computational history of modernism in European literary history: Mapping the Inner Lives of Characters in the European Novel (1840-1920). [PDF]

open access: yesOpen Res Eur, 2023
Radak T   +9 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Willy Haas (1891-1973) : "homme de lettre" [PDF]

open access: yes, 2011
There are many aspects of Haas' life and experiences in India which deserve greater attention. I would like to refer briefly only to his attempts as a litterateur to come to terms with 'India' as presented in his autobiographical recollection and to some
Bhatti, Anil
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

“The case” of Poor Ioanide, or on critical reception in different stages of post-war Romanian literary history [PDF]

open access: yesDiversitate si Identitate Culturala in Europa
This article aims to present some aspects regarding the critical reception of the novel Bietul Ioanide, whose subject is set in the post-war period.
Ana-Maria BĂNICĂ
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

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