Results 81 to 90 of about 8,527,955 (304)

Rushlight: The Literary Supplement, January 23rd 1926

open access: yes, 1926
Wheaton College (Norton, MA) student literary magazine.A Fantasy to be ReadThe Promise UnfulfilledAt the Christening of a SonataWe Call to Your AttentionThunder on the Left by: Christopher MorleyChristina Alberta's FatherGlorious Apollo by: E ...
Katherine Frost   +2 more
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Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Language in City Spaces: The Multisemiotic Significations of Monuments in Nigeria

open access: yesGenealogy
This paper adopts a multisemiotic perspective to examine the significations of monuments in city spaces in Calabar, Nigeria. Data were generated through photo documentation, participant observation and semi-structured interviews in a three-year fieldwork
God’sgift Ogban Uwen   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Literary History

open access: yesPortuguese Literary and Cultural Studies, 2016
ABSTRACT:  Recent changes in the theoretical and practical approaches to literary history: new interest in the relationship among literature, culture, and history, new attention to the narrative quality of this particular genre of history, new interpretations of the traditional problems: distinction between document and monument, distinction between ...
openaire   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

Proceedings of the Manchester Literary and Philosophical Society.

open access: yes, 1878
Mode of access: Internet.1781-1989. 1 v. (Includes index to the Memoirs)Merged with: Memoirs of the Manchester Literary and Philosophical Society; to form: Manchester Literary and Philosophical Society.
Manchester Literary and Philosophical Society.
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Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Florence Hayes Literary Club, yearbook, 1964-1965

open access: yes, 2020
The Florence Hayes Literary Club was a private club dedicated to women's education. This yearbook contains information on officers, meeting schedules and agendas, committee membership lists, and a membership ...
Florence Hayes Literary Club (Toledo, Ohio)
core  

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