Results 81 to 90 of about 341,843 (293)

Cultural identity in literary response:Studying a political poem in different territories [PDF]

open access: yes, 2015
This paper presents research examining the cultural knowledge students draw on when they discuss literary texts. The data suggests the significance of literary study and literary classrooms as spaces where cultural identities are articulated and explored,
Gordon, John
core  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

English Bards and Unknown Reviewers: a Stylometric Analysis of Thomas Moore and the Christabel Review [PDF]

open access: yes, 2015
Fraught relations between authors and critics are a commonplace of literary history. The particular case that we discuss in this article, a negative review of Samuel Taylor Coleridge's Christabel (1816), has an additional point of interest beyond the ...
Benatti, Francesca, Tonra, Justin
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Comparing Two Distribution Models of Paul’s Literary Techniques: Poisson Versus Negative Binomial

open access: yesReligions
This article explores how literary features are statistically distributed in the Christian apostle Paul’s letters. While several decades of occasional research have applied statistics to Paul’s letters, most if not all previous such approaches have ...
Thomas McCauley, Paul Robertson
doaj   +1 more source

History, Literature, and Authority in International Law [PDF]

open access: yes, 2018
One consequence of international law’s recent historical turn has been to sharpen methodological contrasts between intellectual history and international law. Scholars including Antony Anghie, Anne Orford, Rose Parfitt, and Martti Koskenniemi have taken
Christopher Warren
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Littérature et bande dessinée. Enjeux et limites

open access: yesCahiers de Narratologie, 2009
This article deals with two crucial aspects of the encounter between literature and comics, which cannot be reduced to the mere problem of the adaptation of literary texts in comics.
Jan Baetens
doaj   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

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