Results 41 to 50 of about 6,521 (267)

Conspiracy And Populist Narratives in Romanian-Language Contexts: Romania and the Republic of Moldova [PDF]

open access: yesCodrul Cosminului
This paper investigates the discursive interconnections between conspiracy theories and populism in Romanian-language contexts, encompassing both right-wing and left-wing ideologies.
Onoriu Colacel
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

The Relevance of the Reading Process in the Context of Estonian Literary Criticism

open access: yesInterlitteraria, 2020
The importance of the reading experience has been accepted in literary studies ever since the advent of reading-response theories in the 1970s-1980s. Several notable scholars have stressed that meaning is created through the interaction between reader ...
Susanna Soosaar
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Theory-Inspired Rather than Theory-Based Criticism: Towards a Semeiocritical Method for the Interpretation of Literature

open access: yesStudia Anglica Posnaniensia, 2019
The present article is written almost a decade and a half after the reticent announcement of the death of literary theory by a number of scholars around the world.
Besbes Khaled
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Reusing Postmodern Heritage: How Literary Theories Can Help

open access: yesLes Cahiers de la Recherche Architecturale, Urbaine et Paysagère
With the resurgence of interest in postmodern architecture and the need to preserve its built heritage, the challenge arises of effectively updating postmodern buildings without compromising their architectural values.
Maxime Coq, Claudine Houbart
doaj   +1 more source

Critique of Salah Fadl’s "Approach of Realism in Literary Creativity" [PDF]

open access: yesپژوهش‌نامۀ انتقادی متون و برنامه‌های علوم انسانی, 2019
Using a series of criteria, literary criticism is concerned with the study of literary works from the start explaining the works, their elements and concepts, and clarifying their weaknesses and strengths; ultimately, it helps to improve the quality of ...
Fatima Parchekani
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

“A Critical Study on Methods and Protagonists of Literary Criticism by Gino Tellini” [PDF]

open access: yesپژوهش‌نامۀ انتقادی متون و برنامه‌های علوم انسانی, 2018
Literary criticism, as a special branch of humanities and social sciences, is one of the most important topics in foreign literary studies and therefore mostly focused at the universities all around the world.
Fatemeh Asgari
doaj  

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