Results 101 to 110 of about 69,750 (309)

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

On a quest for authenticity to an imaginary place : a narrative analysis of the experiences of British literary tourists

open access: yes, 2015
Literary tourism is a sub-sector of cultural tourism and relates to travelling to places connected to fictional texts and the authors of those texts. Although it is an old form of tourism and lies at the foundation of classic European Grand Tour, it has ...
Amey, Evgenia
core  

Introduction

open access: yesÉtudes Ricoeuriennes / Ricoeur Studies
There is no doubt that for Ricoeur, reading is not an unthought-of act; on the contrary, it is part of his philosophical reflection. Whether it is because he reads the texts of other philosophers, commenting on them extensively, quoting them, or ...
Cristina Henrique da Costa
doaj   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem   +17 more
wiley   +1 more source

Introduction: Toward a history of Soviet and post-Soviet literary theory and criticism

open access: yes, 2011
Introduction: Toward a history of Soviet and post-Soviet literary theory and ...
Dobrenko E., Tihanov G.
core  

Onasemnogene Abeparvovec in Type I Spinal Muscular Atrophy: 24‐Month Follow‐Up From the Italian Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Onasemnogene abeparvovec (OA) is an AAV9‐based gene therapy for spinal muscular atrophy type I (SMA I). Real‐world outcomes show increased response variability compared to clinical trials, and follow‐up data beyond 12–18 months are limited.
Marika Pane   +43 more
wiley   +1 more source

Philosophical Perspectives on Tove Jansson’s "Moominsummer Madness" through Walter Benjamin’s Ideas of Play

open access: yesZagadnienia Rodzajów Literackich
This study examines philosophical perspectives in Tove Jansson’s Moomin novel Moominsummer Madness (MM, 2010 [1954]), with particular attention to the theatrical performance embedded in the narrative. These perspectives are informed by Walter Benjamin’s
Pirjo Suvilehto, Jarosław Płuciennik
doaj   +1 more source

Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce   +72 more
wiley   +1 more source

Literary theory and criticism : an Oxford guide

open access: yes, 2006
Literart Theory and Criticism : An Oxford Guide is unique in its comprehensive coverage. Consisting of 38 essays, written by experts in each field, the volume provides explication, evaluation, and historical contextualization of the theory and practice ...
Timothy Clark   +3 more
core  

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

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